G-quadruplexes constitute a unique class of nucleic acid structures formed by G-rich
oligonucleotides of DNA-or RNA-type. Depending on their chemical nature, loops length …

G-rich nucleic acids can form non-canonical G-quadruplex structures (G4s) in which four
guanines fold in a planar arrangement through Hoogsteen hydrogen bonds. Although many …

Aptamers are single stranded oligonucleotides with specific recognition and binding ability
to target molecules, which can be obtained by Systematic Evolution of Ligands by …

During an epidemic or pandemic, the primary task is to rapidly develop precise diagnostic
approaches and effective therapeutics. Oligonucleotide aptamer-based pathogen detection …

Most viruses express one or several proteins that counter the antiviral defences of the host
cell. This is the task of non-structural protein NS1 in influenza viruses. Absent in the viral …

Zika virus (ZIKV; family Flaviviridae; genus Flavivirus) is a pathogenic mosquito-borne RNA
virus that currently threatens human health in the Americas, large parts of Asia and …

Molecular recognition elements (MREs) can be short sequences of single‐stranded DNA,
RNA, small peptides, or antibody fragments. They can bind to user‐defined targets with high …

We report a selection of a cognate pair of aptamers for whole avian influenza virus particles
of H5N2 by using graphene-oxide based systemic evolution of ligands by exponential …

Enterovirus 71 (EV71) is a major infectious disease affecting millions of people worldwide
and it is the main etiological agent for outbreaks of hand foot and mouth disease (HFMD) …

Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most
important factor in rapidly developing and epidemiologically dangerous diseases, such as …