International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function
HT receptors expressed throughout the human body are targets for established therapeutics
and various drugs in development. Their diversity of structure and function reflects the …
and various drugs in development. Their diversity of structure and function reflects the …
A review of central 5-HT receptors and their function
NM Barnes, T Sharp - Neuropharmacology, 1999 - Elsevier
It is now nearly 5 years since the last of the currently recognised 5-HT receptors was
identified in terms of its cDNA sequence. Over this period, much effort has been directed …
identified in terms of its cDNA sequence. Over this period, much effort has been directed …
The 5-HT3 receptor–the relationship between structure and function
The 5-hydroxytryptamine type-3 (5-HT3) receptor is a cation-selective ion channel of the Cys-
loop superfamily. 5-HT3 receptor activation in the central and peripheral nervous systems …
loop superfamily. 5-HT3 receptor activation in the central and peripheral nervous systems …
The 5-HT3 receptor is present in different subpopulations of GABAergic neurons in the rat telencephalon
M Morales, FE Bloom - Journal of Neuroscience, 1997 - Soc Neuroscience
The type 3 serotonin receptor (5-HT3R) is a ligand-gated ion channel whose presence in the
CNS has been established by radioligand binding, in situ hybridization, and …
CNS has been established by radioligand binding, in situ hybridization, and …
Opioid induced nausea and vomiting
HS Smith, A Laufer - European journal of pharmacology, 2014 - Elsevier
Opioids are broad spectrum analgesics that are an integral part of the therapeutic
armamentarium to combat pain in the palliative care population. Unfortunately, among the …
armamentarium to combat pain in the palliative care population. Unfortunately, among the …
Serotonin receptors and their role in the pathophysiology and therapy of irritable bowel syndrome
Background Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal
tract characterized by abdominal discomfort, pain and changes in bowel habits, often …
tract characterized by abdominal discomfort, pain and changes in bowel habits, often …
On serotonin and migraine: a clinical and pharmacological review
MD Ferrari, PR Saxena - Cephalalgia, 1993 - Wiley Online Library
Migraine patients have chronically low systemic 5‐HT, predisposing them to develop
migrainous headache once an attack has been initiated. Changes in platelet 5‐HT content …
migrainous headache once an attack has been initiated. Changes in platelet 5‐HT content …
Receptors for 5-hydroxytryptamine: current perspectives on classification and nomenclature
GR Martin, PPA Humphrey - Neuropharmacology, 1994 - Elsevier
With the increasing number of 5-HT receptors recently identified, using molecular biology
techniques, the classification of 5-HT receptors is under review. An integrated approach is …
techniques, the classification of 5-HT receptors is under review. An integrated approach is …
Distribution of neurons expressing immunoreactivity for the 5HT3 receptor subtype in the rat brain and spinal cord
M Morales, E Battenberg… - Journal of Comparative …, 1998 - Wiley Online Library
The cellular distribution of the type 3 serotonin receptor (5HT3R) in the rat brain was
established immunocytochemically by using a polyclonal antibody raised against a synthetic …
established immunocytochemically by using a polyclonal antibody raised against a synthetic …
Neurochemistry of the nodose ganglion
H Zhuo, H Ichikawa, CJ Helke - Progress in neurobiology, 1997 - Elsevier
Placode-derived general visceral afferent neurons of the nodose ganglion transmit visceral
sensory information from specialized sensory endings of the vagus nerve and its branches …
sensory information from specialized sensory endings of the vagus nerve and its branches …