Background Mycobacterium tuberculosis is a leading cause of death worldwide. In multi-
drug resistant tuberculosis (MDR-TB) infectiousness is frequently prolonged, jeopardizing …

Extensively drug-resistant (XDR) tuberculosis is defined as disease caused by
Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin, any …

ABSTRACT WHO-endorsed phenotypic drug susceptibility testing (DST) methods for
Mycobacterium tuberculosis are assumed to be the gold standard for identifying rifampin …

Medical microbiology is a branch of medical science that deals with the prevention,
diagnosis, and therapy of infectious diseases. A clinical microbiologist is a professional …

Objectives: To evaluate the performance of three rapid low-cost methods for the detection of
resistance to first-line drugs in Mycobacterium tuberculosis. Methods: One hundred M …

Objectives: With the spread of multidrug-resistant tuberculosis (MDR-TB) there is increasing
demand for new accurate and cost-effective tools for rapid drug susceptibility testing (DST) …

The emergence of multidrug-resistant (MDR)-TB and, more recently, of extensively drug-
resistant (XDR)-TB is a real threat to achieve TB control and elimination. Over 400,000 new …

OBJECTIVE: A multicentre evaluation was performed to assess two rapid low-cost methods,
MTT (3-[4.5-dimethylthiazol-2-yl]-2.5-diphenyltetrazolium bromide) and resazurin assays, for …

Objectives The reference standard methods for drug susceptibility testing (DST) of M.
tuberculosis are very slow to give results, and due to the emergence of multidrug-resistant …

Current methods for drug susceptibility testing of Mycobacterium tuberculosis are either
costly or slow. As the prevalence of multidrug-resistant strains increases, the need for fast …