Efficacy and safety of mecobalamin on peripheral neuropathy: a systematic review and meta-analysis of randomized controlled trials

R Sawangjit, S Thongphui, W Chaichompu… - The Journal of …, 2020 - liebertpub.com
Objectives: To assess the efficacy and safety of mecobalamin on peripheral neuropathy.
Background: Mecobalamin is an active form of vitamin B12 that has been suggested to be …

Exploring targets and therapies for amyotrophic lateral sclerosis: current insights into dietary interventions

ST Ngo, JD Mi, RD Henderson… - Degenerative …, 2017 - Taylor & Francis
A growing number of preclinical and human studies demonstrate a disease-modifying effect
of nutritional state in amyotrophic lateral sclerosis (ALS). The management of optimal …

The Scientific and Therapeutic Rationale for Off‐Label Treatments in Amyotrophic Lateral Sclerosis

R Bedlack, X Li, BA Evangelista… - Annals of …, 2024 - Wiley Online Library
There are no dramatically effective pharmacological treatments for most patients with
amyotrophic lateral sclerosis, a complex disease with multiple underlying mechanisms, such …

[HTML][HTML] Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis

AS Zubair, L Saab, K Scharer, B Khokhar - Brain Circulation, 2024 - journals.lww.com
METHODS: Semi-structured interviews were conducted with the patients and caregivers.
The data was carefully read, coded, and organized into themes and sub-themes by two …

[HTML][HTML] Impaired thiamine metabolism in amyotrophic lateral sclerosis and its potential treatment with benfotiamine: a case report and a review of the literature

RH Mann - Cureus, 2023 - ncbi.nlm.nih.gov
Homogenates of brain tissue from the frontal cortex at autopsy in patients with amyotrophic
lateral sclerosis (ALS) showed dramatically reduced levels of the enzyme thiamine …

Are herbal medicines alone or in combination for diabetic peripheral neuropathy more effective than methylcobalamin alone? A systematic review and meta-analysis

CW Lee, JS Jin, S Kwon, C Jin, SY Cho, SU Park… - … Therapies in Clinical …, 2022 - Elsevier
Abstract Background and purpose In Asian countries, herbal medicines have been used to
treat diabetic peripheral neuropathy (DPN) as an adjunctive therapy. This review aims to …

Use of Off‐Label Drugs and Nutrition Supplements among Patients with Amyotrophic Lateral Sclerosis in Norway

GA Skulstad Johanson, OB Tysnes… - Neurology Research …, 2022 - Wiley Online Library
Background and Objectives. Amyotrophic lateral sclerosis (ALS) is a lethal
neurodegenerative disease, characterized by gradual paralysis and muscle atrophy …

ALSUntangled 41:“Eric Is Winning”

ALSUntangled Group - Amyotrophic Lateral Sclerosis and …, 2018 - Taylor & Francis
Eric Edney, an insurance agent, reportedly experienced his first symptoms of ALS in 1990
and was diagnosed with ALS in 1993 at age 64 years (2, 3). In 1996, after 'gathering all of …

Updates from the fray: rational off-label and over-the-counter prescribing in amyotrophic lateral sclerosis

W Pridmore - RRNMF Neuromuscular Journal, 2021 - journals.ku.edu
Background: Amyotrophic lateral sclerosis (ALS) is a terminal condition, which is increasing
in incidence. Therapeutic interventions have enjoyed limited success. However, research is …

ALSUntangled No. 54:“LEAP2BFIT”

ALSUNTANGLED GROUP - Amyotrophic Lateral Sclerosis and …, 2020 - Taylor & Francis
LEAP2BFIT is a supplement containing many ingredients (ref (2); Version 3.0 ingredients
shown in Figure 1). It is sold as a powder that can be added to water or juice. It is marketed …