Microglial CD74 expression is regulated by TGFβ signaling

J Jahn, A Bollensdorf, C Kalischer, R Piecha… - International Journal of …, 2022 - mdpi.com
Simple Summary In the present study, we provided evidence that TGFβ signaling regulated
the expression of the microglia activation marker CD74. Our data demonstrated that TGFβ1 …

Knockdown of CD44 inhibits proliferation, migration and invasion of osteosarcoma cells accompanied by downregulation of cathepsin S

L Kong, H Ji, X Gan, S Cao, Z Li, Y Jin - Journal of orthopaedic surgery and …, 2022 - Springer
Background Osteosarcoma (OS) is a malignant bone tumour of mesenchymal origin. These
tumours are characterised by rich vascularisation, therefore promoting rapid proliferation …

Identification of cells of leukemic stem cell origin with non-canonical regenerative properties

CG Hollands, AL Boyd, X Zhao, JC Reid, C Henly… - Cell Reports …, 2024 - cell.com
Despite most acute myeloid leukemia (AML) patients entering remission following
chemotherapy, outcomes remain poor due to surviving leukemic cells that contribute to …

Isolation, Identification, Biocontrol Activity, and Plant Growth Promoting Capability of a Superior Strain HM10

M Rehan, AS Alsohim, H Abidou, Z Rasheed… - Polish journal of …, 2021 - sciendo.com
Streptomyces is a genus with known biocontrol activity, producing a broad range of
biologically active substances. Our goal was to isolate local Streptomyces species, evaluate …

MicroRNA-183-5p regulates MITF expression in vitiligo skin depigmentation

AA Al Robaee, AA Alzolibani… - … , Nucleotides & Nucleic …, 2022 - Taylor & Francis
Microphthalmia-associated transcription factor (MITF) is a master regulatory factor for
melanocytes. MITF regulates multiple pigmentary genes for maintaining cellular …

Honey polyphenolic fraction inhibits cyclooxygenase-2 expression via upregulation of microRNA-26a-5p expression in pancreatic islets

SS Ahmed, SF Al Nohair… - European Journal …, 2022 - journals.sagepub.com
Objectives Honey total polyphenolic fraction (HTPF) is reported to have anti-disease
potential, however the role of HTPF in the regulation of microRNAs (miRNAs) has never …

Identification of key genes and biological pathways in chronic obstructive pulmonary disease using bioinformatics and next generation sequencing data analysis

B Vastrad, C Vastrad - bioRxiv, 2024 - biorxiv.org
Identification of accurate biomarkers is still particularly urgent for improving the poor survival
of chronic obstructive pulmonary disease (COPD) patients. In this investigation, we aimed to …