The recent discovery of natural immunity to the hepatitis C virus and vaccine efficacy in the
chimpanzee challenge model has allowed optimism about the development of at least a …

Despite major advances in the understanding and treatment of hepatitis C, a preventive
vaccine remains elusive. The marked genetic diversity and multiple mechanisms of …

Background: The cost-effectiveness of Canada's only supervised injection facility has not
been rigorously evaluated. We estimated the impact of the facility on survival, rates of HIV …

Hepatitis C has a relevant global impact in terms of morbidity, mortality and economic costs,
with more than 70 million people infected worldwide. In the resolution,“Transforming our …

Hepatitis C virus (HCV) infects an estimated more than 150 million people and is a leading
cause of liver disease worldwide. The development of direct-acting antivirals (DAAs) will …

Introduction: With more than 150 million chronically infected people, hepatitis C virus (HCV)
remains a substantial global health burden. Direct-acting antivirals have dramatically …

Abstract Background Hepatitis C virus (HCV) elimination is being seriously considered
globally. Current elimination models require a combination of highly effective HCV treatment …

Introduction: With 3–4 million new infections occurring annually, hepatitis C virus (HCV) is a
major global health problem. There is increasing evidence to suggest that HCV will be …

Abstract Background and Aims Supervised injection facilities (legally sanctioned spaces for
supervised consumption of illicitly obtained drugs) are controversial public health …

Background and Aims The advent of highly effective hepatitis C (HCV) treatments has
questioned the need for a vaccine to control HCV amongst people who inject drugs (PWID) …