Evaluation of injectable nucleus augmentation materials for the treatment of intervertebral disc degeneration
MP Culbert, JP Warren, AR Dixon, HL Fermor… - Biomaterials …, 2022 - pubs.rsc.org
Back pain affects a person's health and mobility as well as being associated with large
health and social costs. Lower back pain is frequently caused by degeneration of the …
health and social costs. Lower back pain is frequently caused by degeneration of the …
Genipin-crosslinked fibrin seeded with oxidized alginate microbeads as a novel composite biomaterial strategy for intervertebral disc cell therapy
Discectomy procedures alleviate disability caused by intervertebral disc (IVD) herniation, but
do not repair herniation-induced annulus fibrosus (AF) defects. Cell therapy shows promise …
do not repair herniation-induced annulus fibrosus (AF) defects. Cell therapy shows promise …
Tissue-mimetic hybrid bioadhesives for intervertebral disc repair
Intervertebral disc (IVD) degeneration and herniation often necessitate surgical interventions
including a discectomy with or without a nucleotomy, which results in a loss of the normal …
including a discectomy with or without a nucleotomy, which results in a loss of the normal …
In situ forming macroporous biohybrid hydrogel for nucleus pulposus cell delivery
AJ Brissenden, BG Amsden - Acta Biomaterialia, 2023 - Elsevier
Degenerative intervertebral disc disease is a common source of chronic pain and reduced
quality of life in people over the age of 40. While degeneration occurs throughout the disc, it …
quality of life in people over the age of 40. While degeneration occurs throughout the disc, it …
Finite element models of intervertebral disc: recent advances and prospects
T Sun, J Wang, X Liu, H Huang, J Wang, M Suo… - Annals of …, 2025 - Taylor & Francis
Objectives The incidence rate of intervertebral disc degeneration (IVDD) is increasing year
by year, which brings great harm to our health. The change of biomechanical factors is an …
by year, which brings great harm to our health. The change of biomechanical factors is an …
Quantifying internal intervertebral disc strains to assess nucleus replacement device designs: a digital volume correlation and ultra-high-resolution MRI study
Introduction: Nucleus replacement has been proposed as a treatment to restore
biomechanics and relieve pain in degenerate intervertebral discs (IVDs). Multiple nucleus …
biomechanics and relieve pain in degenerate intervertebral discs (IVDs). Multiple nucleus …
In situ forming, mechanically resilient hydrogels prepared from 4a-[PEG-b-PTMC-Ac] and thiolated chondroitin sulfate for nucleus pulposus cell delivery
H Riahinezhad, BG Amsden - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Intervertebral disk degeneration (IVDD) is a common condition that causes severe back pain
and affects patients' mobility and life quality considerably. IVDD originates within the central …
and affects patients' mobility and life quality considerably. IVDD originates within the central …
[HTML][HTML] Mitochondria-engine with self-regulation to restore degenerated intervertebral disc cells via bioenergetic robust hydrogel design
J Wang, Y Jiang, C Zhu, Z Liu, L Qi, H Ding, J Wang… - Bioactive Materials, 2024 - Elsevier
Previous studies have confirmed that intervertebral disc degeneration (IDD) is closely
associated with inflammation-induced reactive oxygen species (ROS) and resultant cell …
associated with inflammation-induced reactive oxygen species (ROS) and resultant cell …
碳点-普鲁士蓝纳米酶抗氧化应激延缓椎间盘退变
曹志鹏， 石宇， 李克， 林文正， 姜乐涛， 卜文振， 朱海… - 中国组织工程研究, 2023 - cjter.com
碳点- 普鲁士蓝纳米酶抗氧化应激延缓椎间盘退变 Page 1 4038|中国组织工程研究|第27卷|第
25期|2023年9月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …
25期|2023年9月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …
Comparison of four in vitro test methods to assess nucleus pulposus replacement device expulsion risk
Abstract Background Nucleus replacement devices (NRDs) are not routinely used in clinic,
predominantly due to the risk of device expulsion. Rigorous in vitro testing may enable …
predominantly due to the risk of device expulsion. Rigorous in vitro testing may enable …