Organization of the skin immune system and compartmentalized immune responses in infectious diseases

JAS Quaresma - Clinical microbiology reviews, 2019 - Am Soc Microbiol
The skin is an organ harboring several types of immune cells that participate in innate and
adaptive immune responses. The immune system of the skin comprises both skin cells and …

Human polyomaviruses and cancer: an overview

JCM Prado, TA Monezi, AT Amorim, V Lino, A Paladino… - Clinics, 2018 - SciELO Brasil
The name of the family Polyomaviridae, derives from the early observation that cells infected
with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised …

Characterization of molecular mechanisms driving Merkel cell polyomavirus oncogene transcription and tumorigenic potential

JF Yang, W Liu, J You - PLoS Pathogens, 2023 - journals.plos.org
Merkel cell polyomavirus (MCPyV) is associated with approximately 80% of cases of Merkel
cell carcinoma (MCC), an aggressive type of skin cancer. The incidence of MCC has tripled …

From Merkel cell polyomavirus infection to Merkel cell carcinoma oncogenesis

NA Krump, J You - Frontiers in microbiology, 2021 - frontiersin.org
Merkel cell polyomavirus (MCPyV) infection causes near-ubiquitous, asymptomatic infection
in the skin, but occasionally leads to an aggressive skin cancer called Merkel cell carcinoma …

Infectious entry of Merkel cell polyomavirus

M Becker, M Dominguez, L Greune… - Journal of …, 2019 - Am Soc Microbiol
Merkel cell polyomavirus (MCPyV) is a small, nonenveloped tumor virus associated with an
aggressive form of skin cancer, Merkel cell carcinoma (MCC). MCPyV infections are highly …

[HTML][HTML] Merkel cell polyomavirus and associated Merkel cell carcinoma

JF Yang, J You - Tumour Virus Research, 2022 - Elsevier
Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell
carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate. Since …

Merkel cell polyomavirus infection induces an antiviral innate immune response in human dermal fibroblasts

NA Krump, R Wang, W Liu, JF Yang, T Ma… - Journal of …, 2021 - Am Soc Microbiol
Merkel cell polyomavirus (MCPyV) infects most of the human population asymptomatically,
but in rare cases it leads to a highly aggressive skin cancer called Merkel cell carcinoma …

Characterization of the impact of merkel cell polyomavirus-induced interferon signaling on viral infection

R Wang, JF Yang, TE Senay, W Liu, J You - Journal of Virology, 2023 - Am Soc Microbiol
Merkel cell polyomavirus (MCPyV) has been associated with approximately 80% of Merkel
cell carcinoma (MCC), an aggressive and increasingly incident skin cancer. The link …

[HTML][HTML] Small DNA tumor viruses and human cancer: Preclinical models of virus infection and disease

ME Spurgeon - Tumour Virus Research, 2022 - Elsevier
Human tumor viruses cause various human cancers that account for at least 15% of the
global cancer burden. Among the currently identified human tumor viruses, two are small …

Regulation of polyomavirus transcription by viral and cellular factors

JF Yang, J You - Viruses, 2020 - mdpi.com
Polyomavirus infection is widespread in the human population. This family of viruses
normally maintains latent infection within the host cell but can cause a range of human …