Biologically active azolo-1, 2, 4-triazines and azolopyrimidines

VL Rusinov, VN Charushin, ON Chupakhin - Russian Chemical Bulletin, 2018 - Springer
The review presents current data on the methods of synthesis and biological activity of
purine-isosteric azolo-annulated 1, 2, 4-triazines and pyrimidines with a bridgehead …

An assessment of EGFR and HER2 inhibitors with structure activity relationship of fused pyrimidine derivatives for breast cancer: a brief review

PS Dhiwar, GS Purawarga Matada, R Pal… - Journal of …, 2024 - Taylor & Francis
Epidermal growth factor receptor (EGFR) and its subtype human epidermal growth factor
receptor 2 (HER2) gets activated when its endogenous ligand (s) bind to its ATP binding site …

Fused azoloazines with antidiabetic activity

VL Rusinov, IM Sapozhnikova, AA Spasov… - Russian Chemical …, 2022 - Springer
The purpose of this review is to summarize drugs containing an azoloazine moiety and
exhibiting antidiabetic activity. The review includes azoloazines active against dipeptidyl …

Pyrimido[1,2-a]benzimidazoles: synthesis and perspective of their pharmacological use

VV Fedotov, VL Rusinov, EN Ulomsky… - Chemistry of …, 2021 - Springer
Pyrimido[1,2-a]benzimidazoles: synthesis and perspective of their pharmacological use |
SpringerLink Skip to main content Advertisement SpringerLink Log in Menu Find a journal …

Recent advances in 1, 2, 4-triazolo [1, 5-a] pyrimidine chemistry

G Fischer - Advances in Heterocyclic Chemistry, 2019 - Elsevier
The review deals with the pharmaceutically and agrochemically important group of 1, 2, 4-
triazolo [1, 5-a] pyrimidines (TPs) and covers relevant literature published from about 2006 …

Nitrothiadiazolo [3, 2-a] pyrimidines as promising antiglycating agents

K Savateev, V Fedotov, I Butorin, O Eltsov… - European journal of …, 2020 - Elsevier
Managing the advanced glycation end-products (AGEs) concentration is a reliable approach
to achieve control over the pathogenesis of diabetic vascular complications. Inhibition of …

A review on fused pyrimidine systems as EGFR inhibitors and their structure–activity relationship

TT Yadav, G Moin Shaikh, MS Kumar… - Frontiers in …, 2022 - frontiersin.org
Epidermal growth factor receptor (EGFR) belongs to the family of tyrosine kinase that is
activated when a specific ligand binds to it. The EGFR plays a vital role in the cellular …

Benzimidazoazapurines: design, synthesis, and photophysical study

VV Fedotov, EN Ulomsky, NP Belskaya… - The Journal of …, 2021 - ACS Publications
A highly efficient approach to a new class of polycyclic 8-azapurines, benzo [4, 5] imidazo [1,
2-a][1, 2, 3] triazolo [4, 5-e] pyrimidines (BITPs), with good photophysical characteristics is …

Study of Different Carbonaceous Materials as Modifiers of Screen‐printed Carbon Electrodes for the Triazid as Potential Antiviral Drug

A Ivoilova, N Malakhova, P Mozharovskaia… - …, 2022 - Wiley Online Library
In this work a comparative study of Screen‐Printed Carbon Electrodes (SPCE)–bare and
modified by drop casting with carbonaceous nanomaterials (CNMs) as Multi Walled Carbon …

The synthesis of New 5-R-aminoazolo[1,5-a]pyrimidin-7-ones from an N,S-acetal Derivative of Meldrum's Acid

DN Lyapustin, IV Marusich, DF Fayzullina… - Chemistry of …, 2023 - Springer
A one-step method for the synthesis of new 5-aminoazolo [1, 5-a] pyrimidines was
developed. The use of a synthetic equivalent of carbonyl dielectrophile based on Meldrum's …