Genetics, epigenetics, and transcriptomics of preterm birth

VG Jain, N Monangi, G Zhang… - American Journal of …, 2022 - Wiley Online Library
Preterm birth contributes significantly to neonatal mortality and morbidity. Despite its global
significance, there has only been limited progress in preventing preterm birth. Spontaneous …

The Association Between Maternal Prenatal Hair Cortisol Concentration and Preterm Birth: A Systematic Review and Meta-Analysis

RG Künzel, M Elgazzar, PA Bain, C Kirschbaum… - …, 2024 - Elsevier
Background The risk of preterm birth (PTB) increases when experiencing stress during
pregnancy. Chronic stress has been associated with a dysregulation of the hypothalamic …

Molding influences of prematurity: interviews with adults born preterm

AL D'Agata, M Kelly, CE Green, MC Sullivan - Early human development, 2022 - Elsevier
Background Tremendous medical advancements over the last several decades have
supported the survival of younger and sicker newborns. Substantial quantitative research …

The role of family history of preterm delivery in the individual risk of spontaneous preterm delivery: a case–control study

M Huri, N Strambi, M Finazzi, G Manciucca… - Archives of Gynecology …, 2024 - Springer
Purpose To investigate the role of family history of preterm delivery (PTD) in the individual
risk of spontaneous preterm delivery. Methods A retrospective case–control study was …

The intergenerational association of preterm birth: A systematic review and meta‐analysis

A Seid, MS Cumpston, KY Ahmed… - … Journal of Obstetrics …, 2024 - Wiley Online Library
Background Around half of preterm births lack identifiable causes, indicating the need for
further investigation to understand preterm birth risk factors. Existing studies on the …

[HTML][HTML] Platelet protease activated receptor 4 (PAR 4) receptor genotype is associated with an increased risk of preterm birth

RC Boelig, TJ Cahanap, L Ma, T Zhan… - Journal of Thrombosis …, 2022 - Elsevier
Background Platelet protease activated receptor‐4 (PAR4) Thr120 is a common genetic
variant associated with increased platelet activity. Increased platelet activity is implicated in …

Predicting Preterm Birth Using Proteomics

I Marić, DK Stevenson, N Aghaeepour… - Clinics in …, 2024 - perinatology.theclinics.com
The global prevalence of preterm birth (PTB) has remained mostly unchanged in the decade
between 2010 (at 9.8%) and 2020 (at 9.9%), with approximately 13.4 million infants being …

Predicting preterm birth using electronic medical records from multiple prenatal visits

C Huang, X Long, M van der Ven, M Kaptein… - BMC Pregnancy and …, 2024 - Springer
This study aimed to predict preterm birth in nulliparous women using machine learning and
easily accessible variables from prenatal visits. Elastic net regularized logistic regression …

Recurrent preterm birth risk assessment for two delivery subtypes: A multivariable analysis

I Rattsev, N Flaks-Manov, AC Jelin… - Journal of the …, 2022 - academic.oup.com
Objective The study sought to develop and apply a framework that uses a clinical
phenotyping tool to assess risk for recurrent preterm birth. Materials and Methods We …

[HTML][HTML] Protective Effect of EBF Transcription Factor 1 (EBF1) Polymorphism in Sporadic and Familial Spontaneous Preterm Birth: Insights from a Case-Control Study

T Mladenić, J Wagner, M Kadivnik… - … journal of molecular …, 2024 - pmc.ncbi.nlm.nih.gov
This study investigated the potential role of specific single-nucleotide polymorphisms (SNPs)
in the genes Astrotactin 1 (ASTN1), EBF Transcription Factor 1 (EBF1), Eukaryotic …