Review of the cosolvency models for predicting drug solubility in solvent mixtures: an update

A Jouyban - Journal of Pharmacy & Pharmaceutical …, 2019 - journals.library.ualberta.ca
The cosolvency models frequently used in solubility data modeling of drugs in mixed
solvents were reviewed and their accuracies for calculating the solubility of solutes were …

From the printer to the lungs: Inkjet-printed aerogel particles for pulmonary delivery

C López-Iglesias, AM Casielles, A Altay… - Chemical Engineering …, 2019 - Elsevier
Inkjet printing is as an emerging technique in the biomedical field offering cost-effective
solutions for flexible production and the engineering of personalized medicine solutions …

Oral formulations for preclinical studies: principle, design, and development considerations

Y Gao, C Gesenberg, W Zheng - Developing solid oral dosage forms, 2017 - Elsevier
Abstract Formulation development for preclinical studies is an essential part of the drug
discovery and development process in that it enables pharmacokinetics, efficacy, and safety …

[HTML][HTML] Particulate bioaerogels for respiratory drug delivery

HY Li, C Makatsoris, B Forbes - Journal of Controlled Release, 2024 - Elsevier
The bioaerogel microparticles have been recently developed for respiratory drug delivery
and attract fast increasing interests. These highly porous microparticles have ultralow …

Thermodynamics of the solubility of 4-acetylbenzoic acid in different solvents from 303.15 to 473.15 K

N Sunsandee, M Hronec, M Štolcová… - Journal of Molecular …, 2013 - Elsevier
Solubility data of the solid–liquid equilibrium of 4-acetylbenzoic acid in aqueous and
different organic solvents is essential for industrial design and theoretical studies. The …

[HTML][HTML] Impact of simulated lung fluid components on the solubility of inhaled drugs and predicted in vivo performance

S Radivojev, G Luschin-Ebengreuth, JT Pinto… - International Journal of …, 2021 - Elsevier
Orally inhaled products (OIPs) are gaining increased attention, as pulmonary delivery is a
preferred route for the treatment of various diseases. Yet, the field of inhalation …

Solubility determination and thermodynamic modeling of 2, 4-dinitroaniline in nine organic solvents from T=(278.15 to 318.15) K and mixing properties of solutions

R Xu, A Xu, C Du, Y Cong, J Wang - The Journal of Chemical …, 2016 - Elsevier
Abstract The solubility of 2, 4-dinitroaniline in nine organic solvents of methanol, ethanol,
acetone, acetonitrile, n-propanol, toluene, isopropanol, ethyl acetate and 1-butanol was …

Determination and modeling of the solubility of (limonin in methanol or acetone+ water) binary solvent mixtures at T= 283.2 K to 318.2 K

JP Fan, B Zheng, DD Liao, JX Yu, YH Cao… - The Journal of Chemical …, 2016 - Elsevier
The solubility of limonin in the binary solvent mixtures (methanol+ water) and (acetone+
water) with various initial mole fractions of methanol or acetone was measured by high …

Determination of the solubility, dissolution enthalpy and entropy of N-hydroxymethyl acrylamide in different solvents

Y Li, C Li, L Chen - Journal of Molecular Liquids, 2016 - Elsevier
The solubilities of N-hydroxymethyl acrylamide were measured in pyridine, furan,
acetonitrile, ethyl acetate, butyl acetate, toluene, chloroform, dichloromethane in …

Correlation of solubility of hexamethylene-1, 6-bisthiosulphate disodium salt dihydrate versus dielectric constants of water+ ethanol mixtures

L Song, H Guo, Y Xu, Z Wei, X Zhang, J Ji, C Yang - Fluid Phase Equilibria, 2014 - Elsevier
Abstract The solubilities of hexamethylene-1, 6-bisthiosulphate disodium salt dihydrate
(HTS) in ethanol+ water mixtures were obtained using the laser detection technique at …