Microdissection testicular sperm extraction (microTESE) is considered the gold standard
method for surgical sperm retrieval among patients with non-obstructive azoospermia …

While 7% of the men are infertile, currently, a genetic etiology is identified in less than 25%
of those men, and 30% of the infertile men lack a definitive diagnosis, falling in the …

Highlights•Identifiable genetic abnormalities contribute to 15%–20% of the most severe
forms of male infertility, azoospermia.•Klinefelter syndrome, XXY, is the most common X …

As with many other diseases, genetic testing in human azoospermia was initially restricted to
karyotype analyses (leading to diagnostic chromosome rearrangement tests for Klinefelter …

Men with 47, XYY syndrome present with varying physical attributes and degrees of
infertility. A retrospective chart review was performed on a male infertility and genetic …

Infertility affects approximately 15% of couples, and male factor is responsible for 30%–50%
of all infertility. The most severe form of male infertility is testicular failure, and the typical …

Introduction Thousands of genes are implicated in spermatogenesis, testicular development
and endocrine regulation of testicular function. The genetic contribution to male infertility is …

Abstract 47, XYY syndrome is a sex chromosomal anomaly in men, which may be
associated with infertility and has an incidence of 0.1% of male births. The clinical and …

The World Health Organization (WHO) defines infertility as the inability of a sexually active,
non-contracepting couple to achieve spontaneous pregnancy within one year. Statistics …

An additional Y chromosome occurs in~ 1 in 1,000 males, resulting in the karyotype 47,
XYY. The phenotype includes tall stature, hypotonia, neuropsychiatric comorbidities, and an …