Role of oxidative stress and inflammation-related signaling pathways in doxorubicin-induced cardiomyopathy

S Shi, Y Chen, Z Luo, G Nie, Y Dai - Cell Communication and Signaling, 2023 - Springer
Doxorubicin (DOX) is a powerful and commonly used chemotherapeutic drug, used alone or
in combination in a variety of cancers, while it has been found to cause serious cardiac side …

Curcumin: Overview of extraction methods, health benefits, and encapsulation and delivery using microemulsions and nanoemulsions

MD Ciuca, RC Racovita - International Journal of Molecular Sciences, 2023 - mdpi.com
Curcumin is the principal curcuminoid found in the rhizomes of turmeric. Due to its
therapeutic action against cancer, depression, diabetes, some bacteria, and oxidative stress …

Nanoparticles hitchhike on monocytes for glioblastoma treatment after low-dose radiotherapy

J Kuang, ZY Rao, DW Zheng, D Kuang, QX Huang… - ACS …, 2023 - ACS Publications
Glioblastomas (GBMs) are aggressive primary brain tumors with fatal outcome. Traditional
chemo-radiotherapy has poor therapeutic effect and significant side effects, due to the drug …

Cytotoxic and chemomodulatory effects of Phyllanthus niruri in MCF-7 and MCF-7ADR breast cancer cells

OE Abdel-Sattar, RM Allam, AM Al-Abd, B Avula… - Scientific Reports, 2023 - nature.com
The members of the genus Phyllanthus have long been used in the treatment of a broad
spectrum of diseases. They exhibited antiproliferative activity against various human cancer …

Genistein and/or sulfasalazine ameliorate acetic acid-induced ulcerative colitis in rats via modulating INF-γ/JAK1/STAT1/IRF-1, TLR-4/NF-κB/IL-6, and JAK2/STAT3 …

EA Elhefnawy, HF Zaki, NN El Maraghy… - Biochemical …, 2023 - Elsevier
Ulcerative Colitis (UC) is a chronic idiopathic inflammatory bowel disease in which the
colon's lining becomes inflamed. Exploring herbal remedies that can recover mucosal …

Protection against cancer therapy-induced cardiovascular injury by planed-derived polyphenols and nanomaterials

Y Liao, Q Meng - Environmental Research, 2023 - Elsevier
Cancer therapy-induced heart injury is a significant concern for cancer patients undergoing
chemotherapy, radiotherapy, immunotherapy, and also targeted molecular therapy. The use …

Antibacterial and wound healing applications of curcumin in micro and nano-scaffolds based on chitosan, cellulose, and collagen

M Alavi, MM Zorab, M Ashengroph… - Cellular and Molecular …, 2022 - cellmolbiol.org
About 80% higher risk of amputation resulted from microbial infection was indicated for
patients with diabetic foot ulcers (DFUs). Micro and nano-scaffolds made of natural polymers …

The role of curcumin in the liver-gut system diseases: from mechanisms to clinical therapeutic perspective

T Qin, X Chen, J Meng, Q Guo, S Xu… - Critical Reviews in …, 2024 - Taylor & Francis
Natural products have provided abundant sources of lead compounds for new drug
discovery and development over the past centuries. Curcumin is a lipophilic polyphenol …

Can dietary nutrients prevent cancer chemotherapy-induced cardiotoxicity? an evidence mapping of human studies and animal models

XY Zhang, KL Yang, Y Li, Y Zhao, KW Jiang… - Frontiers in …, 2022 - frontiersin.org
Introduction Chemotherapy has significantly improved cancer survival rates at the cost of
irreversible and frequent cardiovascular toxicity. As the main dose-dependent adverse …

Alloimperatorin from Ammi majus fruits mitigates Piroxicam-provoked gastric ulcer and hepatorenal toxicity in rats via suppressing oxidative stress and apoptosis

HI Abd-Alla, G Ibrahim Fouad, KA Ahmed, K Shaker - Biomarkers, 2022 - Taylor & Francis
ABSTRACT Introduction Fruits of Ammi majus, commonly called bishop's weed, contain a
significant amount of furanocoumarins. Alloimperatorin (Allo, 6) was isolated from the free …