Allogeneic vs. autologous mesenchymal stem/stromal cells in their medication practice

C Li, H Zhao, L Cheng, B Wang - Cell & Bioscience, 2021 - Springer
Mesenchymal stem/stromal cell (MSC)-based therapeutics is already available for treatment
of a range of diseases or medical conditions. Autologous or allogeneic MSCs obtained from …

Targeting adenosine in cancer immunotherapy to enhance T-cell function

S Vigano, D Alatzoglou, M Irving… - Frontiers in …, 2019 - frontiersin.org
T cells play a critical role in cancer control, but a range of potent immunosuppressive
mechanisms can be upregulated in the tumor microenvironment (TME) to abrogate their …

Mesenchymal stromal cells in cancer: a review of their immunomodulatory functions and dual effects on tumor progression

S Galland, I Stamenkovic - The Journal of pathology, 2020 - Wiley Online Library
Mesenchymal stem or stromal cells (MSCs) are pluripotent cells implicated in a broad range
of physiological events, including organogenesis and maintenance of tissue homeostasis as …

The roles of mesenchymal stem cells in tumor inflammatory microenvironment

Z Sun, S Wang, RC Zhao - Journal of hematology & oncology, 2014 - Springer
Tumor behavior is not entirely determined by tumor cells. Studies have demonstrated that a
variety of non-tumor cells in the tumor microenvironment affect tumor behavior; thus, a new …

Mesenchymal stroma: role in osteosarcoma progression

M Cortini, S Avnet, N Baldini - Cancer Letters, 2017 - Elsevier
The initiation and progression of malignant tumors are supported by their microenvironment:
cancer cells per se cannot explain growth and formation of the primary or metastasis, and a …

The future of mesenchymal stem cell-based therapeutic approaches for cancer–from cells to ghosts

A Mohr, R Zwacka - Cancer letters, 2018 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stromal cells which can differentiate into a
variety of cell types including osteoblasts, adipocytes and chondrocytes. They are normally …

Mesenchymal stem cell-derived extracellular vesicles: a novel cell-free therapy

M Jafarinia, F Alsahebfosoul, H Salehi… - Immunological …, 2020 - Taylor & Francis
In recent years, mesenchymal stem/stromal cells (MSCs) have widely been considered as
therapeutic tools in basic researches and clinical trials. Accumulating evidence supports the …

Pre‐treatments enhance the therapeutic effects of mesenchymal stem cells in liver diseases

C Hu, Z Wu, L Li - Journal of Cellular and Molecular Medicine, 2020 - Wiley Online Library
Liver diseases caused by viral infection, alcohol abuse and metabolic disorders can
progress to end‐stage liver failure, liver cirrhosis and liver cancer, which are a growing …

[HTML][HTML] Mesenchymal stem/stromal cells: developmental origin, tumorigenesis and translational cancer therapeutics

C Li, H Zhao, B Wang - Translational oncology, 2021 - Elsevier
While a large and growing body of research has demonstrated that mesenchymal
stem/stromal cells (MSCs) play a dual role in tumor growth and inhibition, studies exploring …

Mesenchymal stem cells used as carrier cells of oncolytic adenovirus results in enhanced oncolytic virotherapy

KJ Mahasa, L De Pillis, R Ouifki, A Eladdadi, P Maini… - Scientific reports, 2020 - nature.com
Mesenchymal stem cells (MSCs) loaded with oncolytic viruses are presently being
investigated as a new modality of advanced/metastatic tumors treatment and enhancement …