Gut microbial metabolites in obesity, NAFLD and T2DM

EE Canfora, RCR Meex, K Venema… - Nature Reviews …, 2019 - nature.com
Evidence is accumulating that the gut microbiome is involved in the aetiology of obesity and
obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin …

Microbial tryptophan catabolites in health and disease

HM Roager, TR Licht - Nature communications, 2018 - nature.com
Accumulating evidence implicates metabolites produced by gut microbes as crucial
mediators of diet-induced host-microbial cross-talk. Here, we review emerging data …

Short-chain fatty acids in control of body weight and insulin sensitivity

EE Canfora, JW Jocken, EE Blaak - Nature Reviews Endocrinology, 2015 - nature.com
The connection between the gut microbiota and the aetiology of obesity and cardiometabolic
disorders is increasingly being recognized by clinicians. Our gut microbiota might affect the …

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

CM Theriot, MJ Koenigsknecht, PE Carlson Jr… - Nature …, 2014 - nature.com
Antibiotics can have significant and long-lasting effects on the gastrointestinal tract
microbiota, reducing colonization resistance against pathogens including Clostridium …

An overview on fecal branched short-chain fatty acids along human life and as related with body mass index: associated dietary and anthropometric factors

D Rios-Covian, S González, AM Nogacka… - Frontiers in …, 2020 - frontiersin.org
Short-chain fatty acids (SCFA) are the main bacterial products of the catabolism of
carbohydrates and proteins in the gut, and their role is essential in host–microbiota …

Physiological implications of hydrogen sulfide: a whiff exploration that blossomed

R Wang - Physiological reviews, 2012 - journals.physiology.org
The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …

p-Cresyl Sulfate

T Gryp, R Vanholder, M Vaneechoutte, G Glorieux - Toxins, 2017 - mdpi.com
If chronic kidney disease (CKD) is associated with an impairment of kidney function, several
uremic solutes are retained. Some of these exert toxic effects, which are called uremic …

Insights into colonic protein fermentation, its modulation and potential health implications

CK Yao, JG Muir, PR Gibson - Alimentary pharmacology & …, 2016 - Wiley Online Library
Background Beneficial effects of carbohydrate fermentation on gastrointestinal health are
well established. Conversely, protein fermentation generates harmful metabolites but their …

Host-microbiome interactions: Gut-Liver axis and its connection with other organs

S Anand, SS Mande - npj Biofilms and Microbiomes, 2022 - nature.com
An understanding of connections between gut microbiome and liver has provided important
insights into the pathophysiology of liver diseases. Since gut microbial dysbiosis increases …

Gut microbiota role in dietary protein metabolism and health-related outcomes: The two sides of the coin

KJ Portune, M Beaumont, AM Davila, D Tomé… - Trends in Food Science …, 2016 - Elsevier
Background Human gut bacteria can synthesize proteinogenic amino acids and produce a
range of metabolites via protein fermentation, some known to exert beneficial or harmful …