Noncanonical functions of the autophagy machinery in pathways including LC3-associated
phagocytosis and LC3-associated endocytosis have garnered increasing interest in both …

Efforts to understand how mitochondrial dysfunction contributes to neurodegeneration have
primarily focussed on the role of mitochondria in neuronal energy metabolism. However …

The objective of this study is to activate autophagy in hepatocellular carcinoma for the
enhancement of its cellular degradation. Liposomes incorporated chitosan in the core used …

Mitophagy neutralizes mitochondrial damage, thereby preventing cellular dysfunction and
apoptosis. Defects in mitophagy have been strongly implicated in age-related …

Infection and inflammation are relevant entities of male reproductive disorders that can lead
to sub-/infertility. Associated damage of the testis of affected men and in rodent models …

Several functions of autophagy associated with proliferation, differentiation, and migration of
endothelial cells have been reported. Due to lack of models recapitulating angiogenic …

L-lactate plays a critical role in learning and memory. Studies in rats showed that
administration of exogenous L-lactate into the anterior cingulate cortex and hippocampus …

The high prevalence of neurodegenerative diseases has become a major public health
challenge and is associated with a tremendous burden on individuals, society and federal …

Degenerative musculoskeletal diseases are structural and functional failures of the
musculoskeletal system, including osteoarthritis, osteoporosis, intervertebral disc …

Tricin, a natural nontoxic flavonoid distributed in grasses and euphorbia plants, has been
reported to scavenge free radicals, possess anti-inflammatory and antioxidative effects …