Stretches of alternating pyrimidine/purines and purines are respectively linked with pathogenicity and growth temperature in prokaryotes

J Bohlin, SP Hardy, DW Ussery - BMC genomics, 2009 - Springer
Background The genomic fractions of purine (RR) and alternating pyrimidine/purine (YR)
stretches of 10 base pairs or more, have been linked to genomic AT content, the formation of …

Interaction of DNA with groove binding ligands

MJ Broome - 2008 - wrap.warwick.ac.uk
Synthetic molecules that target the major groove in a sequence-selective way are a major
goal in molecular medicine. Recently a major step has been taken toward achieving this …