Behavioral and molecular effects induced by cannabidiol and valproate administration in the GASH/Sal model of acute audiogenic seizures
G Cabral-Pereira, D Sánchez-Benito… - Frontiers in behavioral …, 2021 - frontiersin.org
Despite evidence that supports cannabidiol (CBD) as an anticonvulsant agent, there
remains controversy over the antiseizure efficacy, possible adverse effects, and synergistic …
remains controversy over the antiseizure efficacy, possible adverse effects, and synergistic …
Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically audiogenic …
SM Díaz-Rodríguez, MJ Herrero-Turrión… - Frontiers in Molecular …, 2024 - frontiersin.org
Genetic abnormalities affecting glutamate receptors are central to excitatory overload-driven
neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy …
neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy …
Top common differentially expressed genes in the epileptogenic nucleus of two strains of rodents susceptible to audiogenic seizures: WAR and GASH/Sal
S Damasceno, R Gómez-Nieto… - Frontiers in …, 2020 - frontiersin.org
The Wistar Audiogenic Rat (WAR) and the Genetic Audiogenic Seizure Hamster from
Salamanca (GASH/Sal) strains are audiogenic epilepsy models, in which seizures are …
Salamanca (GASH/Sal) strains are audiogenic epilepsy models, in which seizures are …
[HTML][HTML] Morphological and molecular correlates of altered hearing sensitivity in the genetically audiogenic seizure-prone hamster GASH/Sal
D Sánchez-Benito, MA Hyppolito, AJ Alvarez-Morujo… - Hearing Research, 2020 - Elsevier
Rodent models of audiogenic seizures, in which seizures are precipitated by an abnormal
response of the brain to auditory stimuli, are crucial to investigate the neural bases …
response of the brain to auditory stimuli, are crucial to investigate the neural bases …
Proteomic and bioinformatic tools to identify potential hub proteins in the audiogenic seizure-prone hamster GASH/Sal
C García-Peral, MM Ledesma, MJ Herrero-Turrión… - Diagnostics, 2023 - mdpi.com
The GASH/Sal (Genetic Audiogenic Seizure Hamster, Salamanca) is a model of audiogenic
seizures with the epileptogenic focus localized in the inferior colliculus (IC). The sound …
seizures with the epileptogenic focus localized in the inferior colliculus (IC). The sound …
Molecular mechanism analyses of post‐traumatic epilepsy and hereditary epilepsy based on 10× single‐cell transcriptome sequencing technology
F Wen, Z Tan, D Huang, J Xiang - CNS Neuroscience & …, 2024 - Wiley Online Library
Background Single‐cell RNA sequencing analysis has been usually conducted on post‐
traumatic epilepsy (PET) and hereditary epilepsy (HE) patients; however, the transcriptome …
traumatic epilepsy (PET) and hereditary epilepsy (HE) patients; however, the transcriptome …
Expression pattern of ALOXE3 in mouse brain suggests its relationship with seizure susceptibility
HL Tang, SY Chen, H Zhang, P Lu, WW Sun… - Cellular and Molecular …, 2022 - Springer
Arachidonic acid (AA), a polyunsaturated fatty acid, is involved in the modulation of neuronal
excitability in the brain. Arachidonate lipoxygenase 3 (ALOXE3), a critical enzyme in the AA …
excitability in the brain. Arachidonate lipoxygenase 3 (ALOXE3), a critical enzyme in the AA …
Efectos terapéuticos del Cannabidiol en la epilepsia: un estudio preclínico en el modelo animal de epilepsia audiogénica GASH/Sal
GE Cabral Pereira - 2023 - gredos.usal.es
[ES] La epilepsia es una enfermedad presente desde tiempos antiguos en la historia de la
medicina. Se trata de una afección neurológica frecuente que se caracteriza por la …
medicina. Se trata de una afección neurológica frecuente que se caracteriza por la …
Proteomic and metabolomic signature of Dravet Syndrome
N Miljanović - 2021 - edoc.ub.uni-muenchen.de
Dravet syndrome is a rare, severe form of pediatric epilepsy, accompanied by cognitive,
behavioral and motor disturbances. Haploinsufficiency of the Scn1a gene, encoding the …
behavioral and motor disturbances. Haploinsufficiency of the Scn1a gene, encoding the …
[PDF][PDF] Proteomic and metabolomic signature of Dravet Syndrome: analysis in a genetic Scn1a-A1783V mouse model
N Miljanović - 2021 - scholar.archive.org
Dravet syndrome is a rare, severe form of pediatric epilepsy, accompanied by cognitive,
behavioral and motor disturbances. Haploinsufficiency of the Scn1a gene, encoding the …
behavioral and motor disturbances. Haploinsufficiency of the Scn1a gene, encoding the …