Meta-analysis of genome-wide association studies for cattle stature identifies common genes that regulate body size in mammals

AC Bouwman, HD Daetwyler, AJ Chamberlain… - Nature …, 2018 - nature.com
Stature is affected by many polymorphisms of small effect in humans. In contrast, variation in
dogs, even within breeds, has been suggested to be largely due to variants in a small …

Ah receptor pathway intricacies; signaling through diverse protein partners and DNA-motifs

DP Jackson, AD Joshi, CJ Elferink - Toxicology research, 2015 - pubs.rsc.org
Ah receptor pathway intricacies; signaling through diverse protein partners and DNA-motifs -
Toxicology Research (RSC Publishing) DOI:10.1039/C4TX00236A Royal Society of …

Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity

TP Zanos, HA Silverman, T Levy… - Proceedings of the …, 2018 - National Acad Sciences
The nervous system maintains physiological homeostasis through reflex pathways that
modulate organ function. This process begins when changes in the internal milieu (eg …

Vitamin D Induces Interleukin-1β Expression: Paracrine Macrophage Epithelial Signaling Controls M. tuberculosis Infection

M Verway, M Bouttier, TT Wang, M Carrier… - PLoS …, 2013 - journals.plos.org
Although vitamin D deficiency is a common feature among patients presenting with active
tuberculosis, the full scope of vitamin D action during Mycobacterium tuberculosis (Mtb) …

Krüppel-like factors in bone biology

S Zakeri, H Aminian, S Sadeghi… - Cellular signalling, 2022 - Elsevier
The krüppel-like factor (KLF) family is a group of zinc finger transcription factors and
contributes to different cellular processes such as differentiation, proliferation, migration, and …

Stabilization of the Max homodimer with a small molecule attenuates Myc-driven transcription

NB Struntz, A Chen, A Deutzmann, RM Wilson… - Cell chemical …, 2019 - cell.com
The transcription factor Max is a basic-helix-loop-helix leucine zipper (bHLHLZ) protein that
forms homodimers or interacts with other bHLHLZ proteins, including Myc and Mxd proteins …

Dicer in macrophages prevents atherosclerosis by promoting mitochondrial oxidative metabolism

Y Wei, J Corbalán-Campos, R Gurung, L Natarelli… - Circulation, 2018 - Am Heart Assoc
Background: Alternative macrophage activation, which relies on mitochondrial oxidative
metabolism, plays a central role in the resolution of inflammation and prevents …

Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a–LCOR axis

T Celià-Terrassa, DD Liu, A Choudhury, X Hang… - Nature cell …, 2017 - nature.com
Tumour-initiating cells, or cancer stem cells (CSCs), possess stem-cell-like properties
observed in normal adult tissue stem cells. Normal and cancerous stem cells may therefore …

Inhibition of VDAC1 oligomerization blocks cysteine deprivation-induced ferroptosis via mitochondrial ROS suppression

SK Jang, SH Ahn, G Kim, S Kim, J Hong, KS Park… - Cell Death & …, 2024 - nature.com
Ferroptosis, a regulated form of cell death dependent on reactive oxygen species (ROS), is
characterized by iron accumulation and lethal lipid peroxidation. Mitochondria serve as the …

ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility

J van der Raadt, SHC van Gestel… - Nucleic acids …, 2019 - academic.oup.com
Remodeling of chromatin accessibility is necessary for successful reprogramming of
fibroblasts to neurons. However, it is still not fully known which transcription factors can …