Multiscale modeling shows how 2'-deoxy-ATP rescues ventricular function in heart failure
2'-deoxy-ATP (dATP) improves cardiac function by increasing the rate of crossbridge cycling
and Ca 2+ transient decay. However, the mechanisms of these effects and how therapeutic …
and Ca 2+ transient decay. However, the mechanisms of these effects and how therapeutic …
NetSci: A Library for High Performance Biomolecular Simulation Network Analysis Computation
AM Stokely, LW Votapka, MT Hock… - Journal of Chemical …, 2024 - ACS Publications
We present the NetSci program–an open-source scientific software package designed for
estimating mutual information (MI) between data sets using GPU acceleration and a k …
estimating mutual information (MI) between data sets using GPU acceleration and a k …
Modeling cardiac contractile cooperativity across species
MC Childers - Journal of General Physiology, 2025 - rupress.org
Cardiac muscle contraction is replete with cooperative mechanisms (Bremel and Weber,
1972; Murray and Weber, 1981; Tobacman, 1996; Lehrer, 1994; McKillop and Geeves …
1972; Murray and Weber, 1981; Tobacman, 1996; Lehrer, 1994; McKillop and Geeves …
Molecular Micro Modeling of the Heart Muscle
M Prodanovic, N Filipović, SM Mijailovich - In Silico Clinical Trials for …, 2024 - Springer
The understanding of cardiac function and its role in heart diseases can be significantly
advanced through computational modeling of the heart muscle at molecular and …
advanced through computational modeling of the heart muscle at molecular and …
Multiscale modeling and analysis in biophysics
The unprecedented technological advancements seen in recent years have propelled the
field of biophysics to the forefront of biological and medical research. More advanced …
field of biophysics to the forefront of biological and medical research. More advanced …