Astrocytes contribute to the formation, function, and plasticity of synapses. Their processes
enwrap the neuronal components of the tripartite synapse, and due to this close interaction …

Astrocytes, initially described as merely support cells, are now known as a heterogeneous
population of cells actively involved in a variety of biological functions such as: neuronal …

Thyroid hormones (TH s) play key roles in brain development and function. The lack of TH s
during childhood is associated with the impairment of several neuronal connections …

Proper brain neuronal circuitry formation and synapse development is dependent on
specific cues, either genetic or epigenetic, provided by the surrounding neural environment …

Hyperbilirubinemia remains one of the most frequent clinical diagnoses in the neonatal
period. This condition may lead to the deposition of unconjugated bilirubin (UCB) in the …

Gestational hypothyroxinemia, characterized by low levels of maternal thyroxine (T 4) during
gestation, is closely associated with cognitive impairment in offspring. Studies in animal …

Background: Humans and animals are continuously exposed to a number of environmental
substances that act as endocrine disruptors (EDs). While a growing body of evidence is …

Thyroid hormone is a critical modulator of brain metabolism, and it is highly controlled in the
central nervous system. Recent research has uncovered an important role of thyroid …

Congenital hypothyroidism (CH) is an endocrine disease caused by congenital thyroid
hormone (TH) deficiency. MicroRNAs (miRNAs or miRs) have been reported to inhibit the …

Background Accumulating reports evidenced that congenital hypothyroidism (CH) is a kind
of endocrine diseases caused by thyroid hormone imperfection. MicroRNAs (miRNAs) were …