[HTML][HTML] Nanosystems, Drug Molecule functionalization and intranasal delivery: an update on the most promising strategies for increasing the therapeutic efficacy of …
JL Antunes, J Amado, F Veiga, AC Paiva-Santos… - Pharmaceutics, 2023 - mdpi.com
Depression and anxiety are high incidence and debilitating psychiatric disorders, usually
treated by antidepressant or anxiolytic drug administration, respectively. Nevertheless …
treated by antidepressant or anxiolytic drug administration, respectively. Nevertheless …
Use of Esketamine Nasal Spray in Patients with Treatment‐Resistant Depression in Routine Practice: A Real‐World French Study
L Samalin, L Mekaoui, M Rothärmel… - Depression and …, 2024 - Wiley Online Library
Background. The efficacy and safety of esketamine nasal spray (ESK) were established in
registration trials in patients with treatment‐resistant depression (TRD). This French real …
registration trials in patients with treatment‐resistant depression (TRD). This French real …
Long-term remission following esketamine nasal spray sessions in a patient with severe and highly treatment-resistant depression: a single-case report
L Arrighi, E Maakaron, T Korchia… - International Clinical …, 2024 - journals.lww.com
About 30% of patients with major depressive disorder have treatment-resistant depression
(TRD). Recently, intranasal esketamine was approved as a treatment option after the failure …
(TRD). Recently, intranasal esketamine was approved as a treatment option after the failure …
Real-world treatment patterns of patients with major depressive disorder treated with Auvelity in the United States
A Muzyk, FZ Syed, H Zhou, J Cong… - Journal of Medical …, 2024 - Taylor & Francis
Aims Major depressive disorder (MDD) is a prevalent, chronic disorder. Auvelity
(dextromethorphan-bupropion) is a novel, oral N-methyl-D-aspartate (NMDA) receptor …
(dextromethorphan-bupropion) is a novel, oral N-methyl-D-aspartate (NMDA) receptor …
Continuous flow synthesis of N, N-dimethyltryptamine (DMT) analogues with therapeutic potential
A Simoens, A Dejaegere, M Vandevelde… - RSC Medicinal …, 2025 - pubs.rsc.org
Herein, we describe the continuous flow synthesis and in-line extraction of N, N-
dimethyltryptamine (DMT) and several of its analogues using a Fischer indole reaction …
dimethyltryptamine (DMT) and several of its analogues using a Fischer indole reaction …
Synthesis and bioactivity of psilocybin analogues containing a stable carbon–phosphorus bond
M Vandevelde, A Simoens, B Vandekerckhove… - RSC Medicinal …, 2024 - pubs.rsc.org
Psilocybin analogues have been synthesized comprising a non-hydrolysable P–C bond to
evaluate the biological activity and the selectivity towards 5-HT2AR, 5-HT2BR and the TNAP …
evaluate the biological activity and the selectivity towards 5-HT2AR, 5-HT2BR and the TNAP …
Real-world demographic and clinical profiles of patients with treatment-resistant depression initiated on esketamine nasal spray
L Samalin, L Mekaoui, P De Maricourt… - … Journal of Psychiatry …, 2024 - Taylor & Francis
Objective ESKALE is a French, multicentre, observational study of adults with treatment-
resistant depression (TRD) treated with esketamine. This interim analysis describes …
resistant depression (TRD) treated with esketamine. This interim analysis describes …
Mental Health-Related Disability Days and Costs Among Patients with Treatment-Resistant Depression Initiated on Esketamine Nasal Spray and Conventional …
Introduction Treatment-resistant depression (TRD) is related to disproportionate
unemployment and productivity burden in the USA. The current study describes real-world …
unemployment and productivity burden in the USA. The current study describes real-world …
[引用][C] When Still Water Runs Deep: The Complexities of Clinically Repurposing FDA Approved Therapies
P Beninger, J Maron - Clinical Therapeutics, 2022 - clinicaltherapeutics.com
In this month's issue of Clinical Therapeutics, Karkare et al 1 have reported an analysis of
real-world data that heightens the awareness of an increasingly important patient …
real-world data that heightens the awareness of an increasingly important patient …