Fungal endophytes have remarkable potential to produce bioactive compounds with
numerous pharmacological significance that are used in various disease management and …

Aphanamixis polystachya is a medicinal plant of the Meliaceae family and has a rich history
of traditional medicinal use. It is native to Southeast Asia and is commonly found in tropical …

P‑class pumps are specific ion transporters involved in maintaining intracellular/extracellular
ion homeostasis, gene transcription, and cell proliferation and migration in all eukaryotic …

Background Stress ulcer is a severe complication in critically ill patients and causes a high
mortality. The proton pump inhibitor esomeprazole is widely applied in the treatment of …

Phytopathogens have negative impact on crop growth and production. Biological control of
plant pathogens, is a safer alternative to chemical treatments, and may also provide …

We developed a common feature pharmacophore model using known antiadipogenic
compounds (CFPMA). We identified rohitukine, a reported chromone anticancer alkaloid as …

Penyakit ulkus peptikum (PUD) merupakan salah satu gangguan gastrointestinal yang
umum terjadi pada individu berusia 20-50 tahun dengan 1081 kasus kematian (0.08%) di …

Herein we report isolation of a new chromone alkaloid chrotacumine K (12) from fruits and a
chromone glycoside schumaniofioside A (13) from leaves of Dysoxylum binectariferum Hook …

Boldine is the main alkaloid of Peumus boldus Molina, widely used in the traditional
medicine for the treatment of digestive disorders. It is a compound with excellent antioxidant …

Rohitukine is a chromone alkaloid isolated from an Indian medicinal plant Dysoxylum
binectariferum. This natural product has led to the discovery of two clinical candidates …