Protective effects of metformin in various cardiovascular diseases: clinical evidence and AMPK‐dependent mechanisms

Y Bu, M Peng, X Tang, X Xu, Y Wu… - Journal of Cellular …, 2022 - Wiley Online Library
Metformin, a well‐known AMPK agonist, has been widely used as the first‐line drug for
treating type 2 diabetes. There had been a significant concern regarding the use of …

Lycorine protects against septic myocardial injury by activating AMPK-related pathways

H Zhao, Y Chen, L Qian, L Du, X Wu, Y Tian… - Free Radical Biology …, 2023 - Elsevier
Cardiac dysfunction is a common complication in patients with sepsis triggering high
morbidity and mortality. Lycorine (LYC), the main effective monomer component extracted …

Metformin affects cardiac arachidonic acid metabolism and cardiac lipid metabolite storage in a prediabetic rat model

D Miklankova, I Markova, M Hüttl, I Zapletalova… - International Journal of …, 2021 - mdpi.com
Metformin can reduce cardiovascular risk independent of glycemic control. The mechanisms
behind its non-glycemic benefits, which include decreased energy intake, lower blood …

Effect and safety of combined Gegen Qinlian decoction/metformin in the treatment of diabetes mellitus in patients, and its influence on serum C peptide and …

J Chen, Y Xu, Y Zhao, G Liu, J Cui, Y Li, W Li - Tropical Journal of …, 2022 - ajol.info
Purpose: To investigate the clinical efficacy and safety of combined Gegen Qinlian
decoction/metformin in the treatment of diabetes mellitus (DM), and its influence on serum C …

Effects of metformin on ischemia/reperfusion injury: New evidence and mechanisms

E Osorio-Llanes, W Villamizar-Villamizar… - Pharmaceuticals, 2023 - mdpi.com
The search for new drugs with the potential to ensure therapeutic success in the treatment of
cardiovascular diseases has become an essential pathway to follow for health organizations …

[引用][C] Guérir la vieillesse

L Ferry, JM Lemaître - 2022 - humenSciences