Since the first two complete bacterial genome sequences were published in 1995, the science of bacteria has dramatically changed. Using third-generation DNA sequencing, it is …
Genome-scale metabolic models derived from human gut metagenomic data can be used as a framework to elucidate how microbial communities modulate human metabolism and …
Background Several genome-scale metabolic reconstruction software platforms have been developed and are being continuously updated. These tools have been widely applied to …
Cyanobacteria are promising microorganisms for sustainable biotechnologies, yet unlocking their potential requires radical re-engineering and application of cutting-edge synthetic …
Pathway Tools is a bioinformatics software environment with a broad set of capabilities. The software provides genome-informatics tools such as a genome browser, sequence …
PD Karp, SM Paley, M Krummenacker… - Briefings in …, 2010 - academic.oup.com
Pathway Tools is a production-quality software environment for creating a type of model- organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc …
T Weber, HU Kim - Synthetic and Systems Biotechnology, 2016 - Elsevier
Natural products are among the most important sources of lead molecules for drug discovery. With the development of affordable whole-genome sequencing technologies and …
Microbial communities are near universally present in nature. A wealth of meta-omics data has been gathered from numerous ecosystems, such as the human gut, ocean or soil …
WJ Kim, HU Kim, SY Lee - Current Opinion in Systems Biology, 2017 - Elsevier
Genome-scale metabolic models (GEMs) are valuable in describing an organism's entire metabolism using genomic information and have made huge impact on systems biology and …