Melatonin receptors are seven transmembrane‐spanning proteins belonging to the GPCR
superfamily. In mammals, two melatonin receptor subtypes exist‐MT1 and MT2‐encoded by …

Prevention of neurodegenerative diseases is presently a major goal for our Society and
melatonin, an unusual phylogenetically conserved molecule present in all aerobic …

Melatonin, the neurohormone of the pineal gland, is also produced by various other tissues
and cells. It acts via G protein-coupled receptors expressed in various areas of the central …

Melatonin is a neurohormone secreted from the pineal gland and has a wide‐ranging
regulatory and neuroprotective role. It has been reported that melatonin level is disturbed in …

Neurodegenerative diseases are the second most common cause of death and
characterized by progressive impairments in movement or mental functioning in the central …

Background The aging process is not univocal, both body and brain age. Neurological
disorders are a major cause of disability and death worldwide. According to the Global …

The pineal product melatonin has remarkable antioxidant properties. It is secreted during
darkness and plays a key role in various physiological responses including regulation of …

Melatonin, through its different receptors, has pleiotropic functions in mammalian brain.
Melatonin is secreted mainly by the pineal gland and exerts its effects via receptor-mediated …

Melatonin is a pleiotropically acting regulator molecule, which influences numerous
physiological functions. Its secretion by the pineal gland progressively declines by age …

Chronic cerebral hypoperfusion (CCH) is the most common cause of cognitive impairment,
which is commonly found in Alzheimer's disease (AD) and vascular dementia (VaD) …