The COVID-19 pandemic triggered a sense of vulnerability and urgency that led to
concerted actions by governments, funders, regulators and industry to overcome traditional …

Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome historically
characterized by the presence of severe hypoxemia, high-permeability pulmonary edema …

The emergence of a series of SARS-CoV-2 variants has necessitated the search for broad-
spectrum antiviral targets. The aryl hydrocarbon receptor (AhR) senses tryptophan …

Clinical knowledge about SARS-CoV-2 infection mechanisms and COVID-19
pathophysiology have enormously increased during the pandemic. Nevertheless, because …

Long COVID-19 patients show systemic inflammation and persistent symptoms such as
fatigue and malaise, profoundly affecting their quality of life. Since improving oxygenation …

Invasive fungal infections, notably candidemia, have been associated with COVID-19. The
epidemiology of candidemia has significantly changed during the COVID-19 pandemic. We …

The glycosylation of IgG plays a critical role during human severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection, activating immune cells and inducing …

A key issue for research on COVID-19 pathogenesis is the lack of biopsies from patients and
of samples at the onset of infection. To overcome these hurdles, hamsters were shown to be …

Background: Although useful in the time-race against COVID-19, CPAP cannot provide
oxygen over the physiological limits imposed by severe pulmonary impairments. In previous …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
respiratory distress condition known as COVID-19. This disease broadly affects several …