The relationship between Ribosome-associated Quality Control and neurological disorders
J Wang, J Wang, H Cao, Y Xing, Z Wang… - The Journals of …, 2024 - academic.oup.com
Ribosome-associated quality control (RQC), a ubiquitous process essential for maintaining
protein homeostasis in eukaryotes, acts as a critical surveillance system for protein …
protein homeostasis in eukaryotes, acts as a critical surveillance system for protein …
Pharmacological rescue of motor circuit dysfunction in a Drosophila model of paroxysmal dyskinesia
A Wilson, Y Jiang, N Desai, N Simon-Batsford… - bioRxiv, 2024 - biorxiv.org
Background: Paroxysmal dyskinesias (PxDs) are characterised by bouts of involuntary
dystonic and choreiform movements. The patho-mechanisms underlying these debilitating …
dystonic and choreiform movements. The patho-mechanisms underlying these debilitating …
Investigation of epilepsy-related genes in a Drosophila model
X Qu, X Lai, M He, J Zhang, B Xiang, C Liu… - Neural Regeneration … - journals.lww.com
Complex genetic architecture is the major cause of heterogeneity in epilepsy, which poses
challenges for accurate diagnosis and precise treatment. A large number of epilepsy …
challenges for accurate diagnosis and precise treatment. A large number of epilepsy …