Making a good egg: human oocyte health, aging, and in vitro development

EE Telfer, J Grosbois, YL Odey… - Physiological …, 2023 - journals.physiology.org
Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

[HTML][HTML] In vitro growth and maturation of primordial follicles and immature oocytes

EE Telfer, CY Andersen - Fertility and Sterility, 2021 - Elsevier
Cryopreservation of ovarian tissue to preserve the fertility of girls and young women at high
risk of sterility is now widely practiced. Pieces of cryopreserved ovarian cortex can be …

[HTML][HTML] Ovarian follicle culture: advances and challenges for human and nonhuman primates

EE Telfer, MB Zelinski - Fertility and sterility, 2013 - Elsevier
The removal and cryostorage of ovarian cortical biopsies is now offered as a fertility
preservation option for young women. The only available option to restore fertility using this …

[PDF][PDF] Morphological classification of bovine ovarian follicles

RJ Rodgers, HF Irving-Rodgers - Reproduction, 2010 - researchgate.net
Follicle classification is an important aid to the understanding of follicular development and
atresia. Some bovine primordial follicles have the classical primordial shape, but ellipsoidal …

Platelet-rich plasma promotes the development of isolated human primordial and primary follicles to the preantral stage

L Hosseini, A Shirazi, MM Naderi… - Reproductive …, 2017 - Elsevier
This study aimed to assess the effects of platelet-rich plasma (PRP) on growth and survival
of isolated early human follicles in a three-dimensional culture system. After fresh and …

Future developments: in vitro growth (IVG) of human ovarian follicles

EE Telfer - Acta obstetricia et gynecologica Scandinavica, 2019 - Wiley Online Library
Removal and storage of ovarian cortical tissue is currently offered to young female cancer
patients undergoing potentially sterilizing chemotherapy and/or radiotherapy. For patients at …

IGF1R signaling is necessary for FSH-induced activation of AKT and differentiation of human Cumulus granulosa cells

SC Baumgarten, SM Convissar… - The Journal of …, 2014 - academic.oup.com
Context: FSH is routinely administered to in vitro fertilization patients to induce follicle
maturation. During this process, granulosa cells differentiate and acquire specific functional …

Can mammalian mothers influence the sex of their offspring peri-conceptually?

VJ Grant, LW Chamley - Reproduction, 2010 - rep.bioscientifica.com
Fertility preservation is an important type of frontier scientific research in the field of
reproductive health. The culture of ovarian cortices to i) initiate primordial follicle growth and …

[HTML][HTML] Enzymatic isolation of human primordial and primary ovarian follicles with Liberase DH: protocol for application in a clinical setting

J Vanacker, A Camboni, C Dath, A Van Langendonckt… - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To set up a protocol to isolate human preantral follicles with an enzyme
produced in good manufacturing practice conditions for use in a clinical setting. DESIGN …

In vitro development of ovarian follicles

EE Telfer, M McLaughlin - Seminars in reproductive medicine, 2011 - thieme-connect.com
Tissue banking of ovarian material is being increasingly offered to a variety of patients as a
means of fertility preservation. This tissue comprises thin cortical surface biopsies that …