Pathobiology of cognitive impairment in Parkinson disease: challenges and outlooks

KA Jellinger - International Journal of Molecular Sciences, 2023 - mdpi.com
Cognitive impairment (CI) is a characteristic non-motor feature of Parkinson disease (PD)
that poses a severe burden on the patients and caregivers, yet relatively little is known about …

Modulating effects of zingiberaceae phenolic compounds on neurotrophic factors and their potential as neuroprotectants in brain disorders and age-associated …

AM Razak, JK Tan, M Mohd Said, S Makpol - Nutrients, 2023 - mdpi.com
The Zingiberaceae family possess various phenolic compounds that have significant
systemic bioactivities in the brain, including in age-related neurodegenerative diseases …

Functional brain dysconnectivity in Parkinson's disease: a 5‐year longitudinal study

S Yassine, U Gschwandtner, M Auffret… - Movement …, 2022 - Wiley Online Library
Background Tracking longitudinal functional brain dysconnectivity in Parkinson's disease
(PD) is a key element to decoding the underlying physiopathology and understanding PD …

Task‐Related Reorganization of Cognitive Network in Parkinson's Disease Using Electrophysiology

M Bar‐On, S Baharav, Z Katzir, A Mirelman… - Movement …, 2023 - Wiley Online Library
Abstract Background Cognitive deficits in Parkinson's disease (PD) patients are well
described, however, their underlying neural mechanisms as assessed by electrophysiology …

[HTML][HTML] Reduced clinical connectome fingerprinting in multiple sclerosis predicts fatigue severity

L Cipriano, ET Lopez, M Liparoti, R Minino… - NeuroImage: Clinical, 2023 - Elsevier
Background Brain connectome fingerprinting is progressively gaining ground in the field of
brain network analysis. It represents a valid approach in assessing the subject-specific …

Addiction-like alterations of brain activity in recreational video gamers detected via the cue-reactivity fMRI experiment

P Tikhonov, A Levchuk, A Trufanov, A Efimtsev… - Computers in Human …, 2024 - Elsevier
The non-substance addictions are starting to be classified as diseases or disorders, but their
diagnostics strongly rely on questionnaires, making it unclear if there any underlying …

Fading of brain network fingerprint in Parkinson's disease predicts motor clinical impairment

E Troisi Lopez, R Minino, M Liparoti… - Human Brain …, 2023 - Wiley Online Library
The clinical connectome fingerprint (CCF) was recently introduced as a way to assess brain
dynamics. It is an approach able to recognize individuals, based on the brain network. It …

[HTML][HTML] Topological changes of fast large-scale brain dynamics in mild cognitive impairment predict early memory impairment: a resting-state, source reconstructed …

A Romano, ET Lopez, L Cipriano, M Liparoti… - Neurobiology of …, 2023 - Elsevier
Functional connectivity has been used as a framework to investigate widespread brain
interactions underlying cognitive deficits in mild cognitive impairment (MCI). However, many …

Kinematic network of joint motion provides insight on gait coordination: an observational study on Parkinson's disease

ET Lopez, M Liparoti, R Minino, A Romano, A Polverino… - Heliyon, 2024 - cell.com
The analysis of gait kinematics requires to encode and collapse multidimensional
information from multiple anatomical elements. In this study, we address this issue by …

Parkinson's disease-associated genetic variants synergistically shape brain networks

Z Chen, B Wu, G Li, L Zhou, L Zhang, J Liu - medRxiv, 2022 - medrxiv.org
Background Over 90 genetic variants have been found to be associated with Parkinson's
disease (PD) in genome-wide association studies, however, the neural mechanisms of …