Stroke is the second leading cause of death, after ischemic heart disease, and accounts for
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …

In cerebral tissues, due to continuous and high metabolic demand, energy is produced
exclusively by mitochondrial oxidative phosphorylation (OXPHOS). Obstruction of blood flow …

Abstract Significance and Recent Advances: Ischemic stroke is the leading cause of
disability and third in mortality in industrialized nations. Immediate restoration of cerebral …

Despite the clinical reports, few studies have focused on reducing the cardiotoxicity of
cisplatin. In the present study, cardiotoxicity was examined after a single ip injection of …

Despite their clinical benefits in cancer treatment, the deleterious effects on heart following
chemo/radiotherapy are of increasing importance. Zingerone, a natural polyphenol …

Carfilzomib (CFZ) is an anticancer medication acting as a selective proteasome inhibitor.
However, it can cause cardiovascular problems, increasing mortality and morbidity. This …

The aim of this study was to investigate possible protective effects of apocynin (APO), an
NADPH oxidase (NOX2) inhibitor, on cisplatin (CIS)‐induced testicular damage. Four …

Significance: Phagocytes play a key role in promoting the oxidative stress after ischemic
stroke occurrence. The phagocytic NADPH oxidase (NOX) 2 is a membrane-bound enzyme …

Background: the aim of this study was to investigate the effects of apocynin (APO) on
hormone levels, the blood-testis barrier, and oxidative biomarkers in monosodium glutamate …

Purpose: This experimental study was designed to explore the protective effect of apocynin,
the NADPH-oxidase inhibitor, on kidney damage induced by ischemia/reperfusion (I/R) in a …