Dopamine receptors are widely distributed within the brain where they play critical
modulator roles on motor functions, motivation and drive, as well as cognition. The …

Anhedonia is one of the core symptoms of major depressive disorder (MDD), which is often
inadequately treated by traditional antidepressants. The modern framework of anhedonia …

Changes in cognition, affect, and brain function combine to promote a shift in the nature of
mentation in older adulthood, favoring exploitation of prior knowledge over exploratory …

Pleasure is a fundamental driver of human behaviour, yet its neural basis remains largely
unknown. Rodent studies highlight opioidergic neural circuits connecting the nucleus …

In the past decade, decision neuroscience and neuroeconomics have developed many new
insights in the study of decision making. This review provides an overarching update on how …

Opioid receptors are expressed throughout the brain and play a major role in regulating
striatal dopamine (DA) release. Clinical studies have shown that naloxone (NAL, a …

Dopamine signaling plays a critical role in shaping brain functional network organization
and behavior. Prominent theories suggest the relative expression of D1-to D2-like dopamine …

As humans are social beings, human behavior and cognition are fundamentally shaped by
information provided by peers, making human subjective value for rewards prone to be …

In traditional offline health-seeking behavior, patients consistently exhibit a preference for
similar types of physicians due to limited access to physicians' information. Nevertheless …

As a non-invasive imaging tool, positron emission tomography (PET) plays an important role
in brain science and disease research. Dynamic acquisition is one way of brain PET …