Recent methodological and instrumental advances in solution-state nuclear magnetic
resonance have opened up the way to investigating challenging problems in structural …

Solving structures of native oligomeric protein complexes using traditional high-resolution
NMR techniques remains challenging. However, increased utilization of computational …

Water dynamics in the hydration layers of biomolecules play crucial roles in a wide range of
biological functions. A hydrated protein contains multiple components of diffusional and …

Large molecules, such as membrane proteins, play crucial roles in various biologically
important events. We have developed the transferred cross-saturation (TCS) method, which …

One of the main prerequisites for the successful design of bioactive molecules and drugs is
the elucidation of the three-dimensional structure of small molecular ligands, receptors and …

NMR is a unique methodology for obtaining information about the conformational dynamics
of proteins in heterogeneous biomolecular systems. In various NMR methods, such as …

Protein–protein interactions are necessary for various cellular processes, and therefore,
information related to protein–protein interactions and structural information of complexes is …

Protein–ligand interactions on liquid–solid interfaces governed the design of functional
biomaterials. However, accurate residue details of ligand induced protein binding and …

We have developed an open-source cross-platform software toolkit entitled ACCEPT-NMR
(Automated Crystal Contact Extrapolation/Prediction Toolkit for NMR) as a helpful tool to …

Different instruments are being used to determine the qualitative and quantitative
parameters in various food applications, but rapid and noninvasive analytical methodologies …