Protein-based therapeutics represent a rapidly growing segment of approved disease
treatments. Successful intracellular delivery of proteins is an important precondition for …

Case-control studies are commonly used to evaluate effectiveness of licensed vaccines after
deployment in public health programs. Such studies can provide policy-relevant data on …

Haemophilus influenzae serotype b (Hib) was previously the most common cause of
bacterial meningitis and an important etiologic agent of pneumonia in children aged< 5 …

Vaccines have already saved many lives and they have the potential to save many more as
increasingly elaborate technologies deliver new and effective vaccines against both …

As more new and improved vaccines become available, decisions on which to adopt into
routine programmes become more frequent and complex. This qualitative study aimed to …

Background Competing priorities make using a transparent and evidence-based approach
important when deciding to recommend new vaccines. We conducted a literature review to …

Despite the fact that the incidence and mortality rates due to dengue virus (DENV) infection
in Indonesia are relatively high, dengue vaccination has not yet been introduced. This study …

H. influenzae serotype b (Hib) used to be the commonest cause of bacterial meningitis in
young children. The widespread use of Hib conjugate vaccine has profoundly altered the …

The decision-making process to introduce new vaccines into national immunization
programmes is often complex, involving many stakeholders who provide technical …

The case-control methodology is frequently used to evaluate vaccine effectiveness post-
licensure. The results of such studies provide important insight into the level of protection …