Streptomyces: Still the Biggest Producer of New Natural Secondary Metabolites, a Current Perspective

L Donald, A Pipite, R Subramani, J Owen… - Microbiology …, 2022 - mdpi.com
There is a real consensus that new antibiotics are urgently needed and are the best chance
for combating antibiotic resistance. The phylum Actinobacteria is one of the main producers …

Polyene macrolide biosynthesis in streptomycetes and related bacteria: recent advances from genome sequencing and experimental studies

P Caffrey, E De Poire, J Sheehan… - Applied microbiology and …, 2016 - Springer
The polyene macrolide group includes important antifungal drugs, to which resistance does
not arise readily. Chemical and biological methods have been used in attempts to make …

Vibrio parahaemolyticus: Exploring its Incidence in Malaysia and the Potential of Streptomyces sp. as an Anti-Vibrio Agent

KY Loo, LTH Tan, JWF Law… - … In Microbes & …, 2023 - journals.hh-publisher.com
As the world recovers from the COVID-19 pandemic, concern remains for future potential
outbreaks because of the persisting effects of climate change, including the proliferation of …

Antagonistic activity and mechanism of an isolated Streptomyces corchorusii stain AUH-1 against phytopathogenic fungi

Y Yang, S Zhang, K Li - World Journal of Microbiology and Biotechnology, 2019 - Springer
The various diseases that occur during the growth of plants usually cause a significant
reduction in production and quality of agricultural products. Actinomycetes, especially …

Isolation and evaluation of rhizosphere actinomycetes with potential application for biocontrolling Fusarium wilt of banana caused by Fusarium oxysporum f. sp …

L Zhang, H Zhang, Y Huang, J Peng, J Xie… - Frontiers in …, 2021 - frontiersin.org
Fusarium wilt of banana caused by Fusarium oxysporum f. sp. cubense tropical race 4 (TR4)
is globally one of the most destructive soil-borne fungal diseases. Biological control using …

Effects of addition of elicitors on rimocidin biosynthesis in Streptomyces rimosus M527

Z Song, Z Ma, A Bechthold, X Yu - Applied microbiology and biotechnology, 2020 - Springer
The polyene macrolide rimocidin, produced by Streptomyces rimosus M527, is highly
effective against a broad range of fungal plant pathogens, but at low yields. Elicitation is an …

Identification of RimR2 as a positive pathway-specific regulator of rimocidin biosynthesis in Streptomyces rimosus M527

H Li, Y Hu, Y Zhang, Z Ma, A Bechthold, X Yu - Microbial cell factories, 2023 - Springer
Background Streoptomyces rimosus M527 is a producer of the polyene macrolide rimocidin
which shows activity against various plant pathogenic fungi. Notably, the regulatory …

Antagonistic activity of a novel antifungalmycin N2 from Streptomyces sp. N2 and its biocontrol efficacy against Rhizoctonia solani

Z Wu, Y Yang, K Li - FEMS Microbiology Letters, 2019 - academic.oup.com
ABSTRACT Antifungalmycin N2 (3-methyl-3, 5-amino-4-vinyl-2-pyrone, C6H7O2N) is a
novel bioactive substance produced by Streptomyces sp. N2. In this present work, the …

Sequential improvement of rimocidin production in Streptomyces rimosus M527 by introduction of cumulative drug-resistance mutations

Y Zhao, Z Song, Z Ma, A Bechthold… - Journal of Industrial …, 2019 - academic.oup.com
Rimocidin is a polyene macrolide that exhibits a strong inhibitory activity against a broad
range of plant-pathogenic fungi. In this study, fermentation optimization and ribosome …

Investigating the plant growth promoting and biocontrol potentiality of endophytic Streptomyces SP. SP5 against early blight in Solanum lycopersicum seedlings

S Devi, M Sharma, RK Manhas - BMC microbiology, 2022 - Springer
Background Early blight (EB), caused by Alternaria solani, is one of the alarming diseases
that restrict tomato production globally. Existing cultural practices and fungicide applications …