Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy
L Yang, Z Chu, M Liu, Q Zou, J Li, Q Liu… - Journal of hematology & …, 2023 - Springer
Amino acids are basic nutrients for immune cells during organ development, tissue
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …
[HTML][HTML] NK cell-based tumor immunotherapy
H Zhang, L Yang, T Wang, Z Li - Bioactive materials, 2024 - Elsevier
Natural killer (NK) cells display a unique inherent ability to identify and eliminate virus-
infected cells and tumor cells. They are particularly powerful for elimination of hematological …
infected cells and tumor cells. They are particularly powerful for elimination of hematological …
SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency
L Schmied, TT Luu, JN Søndergaard, SH Hald… - Science …, 2023 - science.org
Natural killer (NK) cells recognize virally infected cells and tumors. NK cell function depends
on balanced signaling from activating receptors, recognizing products from tumors or …
on balanced signaling from activating receptors, recognizing products from tumors or …
Enhanced anticancer efficacy of primed natural killer cells via coacervate-mediated exogenous interleukin-15 delivery
Effective exogenous delivery of interleukin (IL)-15 to natural killer (NK) cells with subsequent
anticancer efficacy could be a promising immune cell-based cancer immunotherapy. For the …
anticancer efficacy could be a promising immune cell-based cancer immunotherapy. For the …
[图书][B] Innate Lymphoid Cell Development, Migration, and Function
P Licona-Limón, J Henao-Mejia, JC Crispín - 2023 - books.google.com
Cell lineages derived from common lymphoid progenitors (CLPs) play a critical role in
antigen recognition, acute and long term protection against pathogens, and maintenance of …
antigen recognition, acute and long term protection against pathogens, and maintenance of …
Control of NK cell tolerance in MHC class I-deficiency by regulated SHP-1 localization to the activating immune synapse
L Schmied, TT Luu, JN Søndergaard, S Meinke… - Biorxiv, 2022 - biorxiv.org
Signaling via inhibitory KIR/Ly49 receptors preserves natural killer (NK) cell self-tolerance
but also conveys NK cell reactivity towards MHC class-I low target cells in an education …
but also conveys NK cell reactivity towards MHC class-I low target cells in an education …
FOXO1 and FOXO3 cooperatively regulate innate lymphoid cell development
TT Luu, JN Søndergaard, L Peña-Pérez… - Frontiers in …, 2022 - frontiersin.org
Natural killer (NK) cells play roles in viral clearance and early surveillance against malignant
transformation, yet our knowledge of the underlying mechanisms controlling their …
transformation, yet our knowledge of the underlying mechanisms controlling their …
Soluble and Exosome-Bound α-Galactosylceramide Mediate Preferential Proliferation of Educated NK Cells With Increased Anti-Tumor Capacity
AK Wagner, U Gehrmann, S Hiltbrunner, V Carannante… - Cancers, 2021 - mdpi.com
Simple Summary Many cancers down-regulate the expression of major histocompatibility
complex class I (MHC-I) to avoid recognition and elimination by the adaptive immune …
complex class I (MHC-I) to avoid recognition and elimination by the adaptive immune …
[PDF][PDF] Soluble and Exosome-Bound α-Galactosylceramide Mediate Preferential Proliferation of Educated NK Cells with Increased Anti-Tumor Capacity. Cancers 2021 …
AK Wagner, U Gehrmann, S Hiltbrunner, V Carannante… - 2021 - researchgate.net
Natural killer (NK) cells can kill target cells via the recognition of stress molecules and down-
regulation of major histocompatibility complex class I (MHC-I). Some NK cells are educated …
regulation of major histocompatibility complex class I (MHC-I). Some NK cells are educated …