• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Hypertensive emergencies (HE) represent high cardiovascular risk situations defined by a
severe increase in blood pressure (BP) associated with acute, hypertension mediated organ …

Introduction Acute limb ischemia is a rare but serious condition that carries with it a high rate
of morbidity and mortality. Objective This review highlights the pearls and pitfalls of acute …

Abstract In the Emergency Medicine setting, D-dimer is currently employed in the diagnostic
assessment of suspected venous thromboembolism and aortic syndrome. The nonspecific …

Non-traumatic thoracic aorta emergencies are associated with significant morbidity and
mortality. Diseases of the intimomedial layers (aortic dissection and variants) have been …

Background Diagnosis of acute aortic syndrome is challenging and associated with high
perihospital mortality rates. The study aim was to evaluate current pathways and understand …

Aortic dissection (AD) is a critical cardiovascular condition with the potential for devastating
consequences. This study evaluated the histological changes in the aorta wall in patients …

Kartavya Sharma is an assistant professor in the Departments of Neurology and
Neurological Surgery at the University of Texas Southwestern Medical Center, Dallas, where …

Background T helper (Th) cells are closely involved in vascular inflammation, endothelial
dysfunction, and atherogenesis, which are the hallmarks of aortic dissection (AD). This study …

Acute aortic syndromes (AASs) are severe conditions defined by dissection, hemorrhage,
ulceration or rupture of the thoracic aorta. AASs share etiological and pathophysiological …