Genetic variability and evolution of hepatitis E virus

PP Primadharsini, S Nagashima, H Okamoto - Viruses, 2019 - mdpi.com
Hepatitis E virus (HEV) is a single-stranded positive-sense RNA virus. HEV can cause both
acute and chronic hepatitis, with the latter usually occurring in immunocompromised …

Review of Hepatitis E Virus in Rats: Evident Risk of Species Orthohepevirus C to Human Zoonotic Infection and Disease

G Reuter, Á Boros, P Pankovics - Viruses, 2020 - mdpi.com
Hepatitis E virus (HEV)(family Hepeviridae) is one of the most common human pathogens,
causing acute hepatitis and an increasingly recognized etiological agent in chronic hepatitis …

Orthohepevirus C: An Expanding Species of Emerging Hepatitis E Virus Variants

B Wang, D Harms, XL Yang, CT Bock - Pathogens, 2020 - mdpi.com
Hepatitis E virus (HEV) is an emerging zoonotic pathogen that has received an increasing
amount of attention from virologists, clinicians, veterinarians, and epidemiologists over the …

Rocahepevirus ratti as an Emerging Cause of Acute Hepatitis Worldwide

S Benavent, S Carlos, G Reina - Microorganisms, 2023 - mdpi.com
The hepatitis E virus (HEV) is a widespread human infection that causes mainly acute
infection and can evolve to a chronic manifestation in immunocompromised individuals. In …

Rat hepatitis E virus: presence in humans in South-Western France?

D Parraud, S Lhomme, JM Péron, I Da Silva… - Frontiers in …, 2021 - frontiersin.org
Background: Hepatitis E Virus (HEV) is one of the most common causes of hepatitis
worldwide, and South-Western France is a high HEV seroprevalence area. While most …

First detection and characterization of rat hepatitis E Virus (HEV-C1) in Japan

M Takahashi, S Kunita, M Kawakami, T Kadosaka… - Virus Research, 2022 - Elsevier
Rat hepatitis E virus (HEV-C1) in the Orthohepevirus C species has been reported to cause
zoonotic infection and hepatitis in humans. HEV-C1 strains have been detected from wild …

Multivesicular body sorting and the exosomal pathway are required for the release of rat hepatitis E virus from infected cells

PP Primadharsini, S Nagashima, M Takahashi… - Virus research, 2020 - Elsevier
Recent reports have shown that rat hepatitis E virus (HEV) is capable of infecting humans.
We also successfully propagated rat HEV into human PLC/PRF/5 cells, raising the possibility …

Genomic and spatial variability of a European common vole hepevirus

R Ryll, G Heckel, VM Corman, JF Drexler, RG Ulrich - Archives of virology, 2019 - Springer
Rodents host different orthohepeviruses, namely orthohepevirus C genotype HEV-C1 (rat
hepatitis E virus, HEV) and the additional putative genotypes HEV-C3 and HEV-C4. Here …

Characterization of a Novel Rat Hepatitis E Virus Isolated from an Asian Musk Shrew (Suncus murinus)

H Bai, W Li, D Guan, J Su, C Ke, Y Ami, Y Suzaki… - Viruses, 2020 - mdpi.com
The Asian musk shrew (shrew) is a new reservoir of a rat hepatitis E virus (HEV) that has
been classified into genotype HEV-C1 in the species Orthohepevirus C. However, there is …

Production of capsid proteins of rat hepatitis E virus in Escherichia coli and characterization of self-assembled virus-like particles

T Kobayashi, M Takahashi, S Ohta, S Nagashima… - Virus Research, 2021 - Elsevier
Rat hepatitis E virus (HEV) has been isolated from wild rats worldwide and the potential of
zoonotic transmission has been documented. Escherichia coli (E. coli) is utilized as an …