The inter-individual differences in cancer susceptibility are somehow correlated with the
genetic differences that are caused by the polymorphisms. These genetic variations in drug …

Simple Summary Tamoxifen is an important adjuvant endocrine therapy in estrogen receptor
(ER)-positive breast cancer patients. It is mainly catalyzed by the enzyme CYP2D6 into the …

Tamoxifen is commonly prescribed for preventing recurrence in patients with breast cancer.
However, the responses of the patients on tamoxifen treatment are variable. Cytochrome …

Tamoxifen (TAM) is used in treatment of hormonal dependent breast cancer, both in
premenopausal and postmenopausal women. TAM is intrinsically metabolized by CYP450 …

Pharmacogenomics has become integral to personalised medicine in breast cancer,
utilising genetic insights to customize treatment strategies and enhance patient outcomes …

Background: Although tamoxifen is a main adjuvant therapy in estrogen positive breast
cancer especially in premenopausal women, reliance on genetic polymorphisms of its …

Tamoksifen je hormonska terapija koja se koristi u liječenju i prevenciji karcinoma dojke
ovisnih o estrogenu. Karcinomi dojke ovisni o estrogenu maligni su tumori koji na svojim …