Immunotherapy of multiple myeloma: current status as prologue to the future

HN Abramson - International Journal of Molecular Sciences, 2023 - mdpi.com
The landscape of therapeutic measures to treat multiple myeloma has undergone a seismic
shift since the dawn of the current century. This has been driven largely by the introduction of …

Bispecific antibodies for the management of relapsed/refractory multiple myeloma

P Tacchetti, S Barbato, K Mancuso, E Zamagni, M Cavo - Cancers, 2024 - mdpi.com
Simple Summary Bispecific antibodies (BsAbs) provide a new mode of targeting multiple
myeloma (MM) plasma cells (PCs), basing their action on the activation and redirection of …

Advancements in Bispecific Antibodies for Multiple Myeloma: What's New and What Lies Ahead

TH Mouhieddine, BA Costa, J Richter - Seminars in Hematology, 2024 - Elsevier
Recent advancements in multiple myeloma (MM) treatment—including immunomodulatory
drugs, proteasome inhibitors, monoclonal antibodies, and T cell–redirecting therapies like …

Antibody-drug conjugates, bispecific antibodies and CAR-T cells therapy in multiple myeloma

P Tacchetti, M Talarico, S Barbato… - Expert Review of …, 2024 - Taylor & Francis
Introduction Modern immunotherapy approaches are revolutionizing the treatment scenario
of relapsed/refractory (RR) multiple myeloma (MM) patients, providing an opportunity to …

Immunotherapy in multiple myeloma

PA Cantó, MA Herraiz, J de la Rubia Comos - Medicina Clínica (English …, 2024 - Elsevier
Patients with multiple myeloma who present with refractory disease or relapse after
receiving the main classes of available drugs–immunomodulators, proteasome inhibitors …

Inmunoterapia en el mieloma múltiple

PA Cantó, MA Herraiz, J de la Rubia Comos - Medicina Clínica, 2024 - Elsevier
Los pacientes con mieloma múltiple que presentan una enfermedad refractaria o en recaída
tras recibir las principales clases de fármacos disponibles—inmunomoduladores …

[PDF][PDF] Challenges in Multiple Myeloma Therapy in Older and Frail Patients

A Aureli, B Marziani, T Sconocchia, G Pasqualone… - 2025 - preprints.org
Every year, more than 150,000 cases of multiple myeloma (MM) are diagnosed worldwide,
and over 100,000 deaths caused by this malignancy are recorded. MM incidence is …

[HTML][HTML] T-Cell Engagers Emerge Across Cancer Settings

B Mueller - 2023 - targetedonc.com
T-Cell Engagers Emerge Across Cancer Settings NEWS All NewsFDA BriefsOncology IconsSpecial
ReportsVoices from the Field CONFERENCES Conference CoverageConference ListingData …

REGN545 Spurs Positive Responses in R/R Myeloma.

C Seymour - Targeted Therapies in Oncology, 2023 - go.gale.com
Using the bispecific antibody REGN5459 in multiple myeloma resulted in durable, deep, and
dose-dependent responses in patients with relapsed/refractory multiple myeloma, according …

[HTML][HTML] Bispecific Antibodies in Multiple Myeloma

CH Weaver - news.cancerconnect.com
Bispecific antibody constructs represent an innovative immunotherapy approach that helps
the body's immune system target cancer cells and appears very promising for the treatment …