Genetic analysis of right heart structure and function in 40,000 people
Congenital heart diseases often involve maldevelopment of the evolutionarily recent right
heart chamber. To gain insight into right heart structure and function, we fine-tuned deep …
heart chamber. To gain insight into right heart structure and function, we fine-tuned deep …
Using Machine Learning to Elucidate the Spatial and Genetic Complexity of the Ascending Aorta
Background The left ventricular outflow tract (LVOT) and ascending aorta are spatially
complex, with distinct pathologies and embryologic origins. Prior work examined genetics of …
complex, with distinct pathologies and embryologic origins. Prior work examined genetics of …
Genetic determinants of interventricular septal anatomy and the risk of ventricular septal defects and hypertrophic cardiomyopathy
Background The interventricular septum (IVS) plays a primary role in cardiovascular
physiology and a large proportion of genetic risk remains unexplained for structural heart …
physiology and a large proportion of genetic risk remains unexplained for structural heart …