Changes in mRNA stability and translation are critical control points in the regulation of gene
expression, particularly genes encoding growth factors, inflammatory mediators, and proto …

Despite considerable amount of research, the poor prognosis of patients diagnosed with
glioblastoma multiforme (GBM) critically needs new drug development to improve clinical …

AU-rich element-binding proteins (ARE-BP) regulate the stability and/or translational
efficiency of mRNAs containing cognate binding sites. Many targeted transcripts encode …

Messenger RNA decay is a critical mechanism to control the expression of many
inflammation-and cancer-associated genes. These transcripts are targeted for rapid …

Adenylate‐and uridylate‐rich element (ARE) motifs are cis‐acting elements present in the
3′ untranslated region of mRNA transcripts that encode many inflammation‐and cancer …

A considerable number of genes that code for AU-rich mRNAs including cytokines, growth
factors, transcriptional factors, and certain receptors are involved in both chronic …

Abstract p38α mitogen-activated protein kinase (MAPK) is activated in cancer cells in
response to environmental factors, oncogenic stress, radiation, and chemotherapy. p38α …

Post‐transcriptional control of gene expression is aberrant in cancer cells. Sustained
stabilization and enhanced translation of specific mRNAs are features of tumor cells. AU …

Glioblastoma (GBM) is a deadly and the most common primary brain tumor in adults. Due to
their regulation of a high number of mRNA transcripts, microRNAs (miRNAs) are key …

Defects in AU-rich elements (ARE)-mediated posttranscriptional control can lead to several
abnormal processes that underlie carcinogenesis. Here, we performed a systematic analysis …