A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

The release of reactive oxygen species (ROS) and the generation of oxidative stress are
considered critical factors for the pathogenesis of diabetes mellitus (DM), a disorder that is …

Neurodegenerative disorders are significantly increasing in incidence as the age of the
global population continues to climb with improved life expectancy. At present, more than 30 …

Synaptic dysfunction is widely proposed as an initial insult leading to the neurodegeneration
observed in Alzheimer's disease (AD). We hypothesize that the initial insult originates in the …

Wingless-type mouse mammary tumor virus (MMTV) integration site (Wnt) signaling is one of
the most critical pathways in developing and adult tissues. In the brain, Wnt signaling …

Wnt pathway is involved in synaptic plasticity and neuronal survival, and alterations in Wnt
signaling have previously been reported both in aging and neurodegenerative diseases …

The Wnt/β-catenin signaling is a conserved pathway that has a crucial role in embryonic and
adult life. Dysregulation of the Wnt/β-catenin pathway has been associated with diseases …

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are found in familial and
idiopathic cases of Parkinson's disease (PD), but are also associated with immune-related …

Acute as well as chronic disorders of the nervous system lead to significant morbidity and
mortality for millions of individuals globally. Given the ability to govern stem cell proliferation …

Wnt/β-catenin signaling is required for specification and neurogenesis of midbrain
dopaminergic (mDA) neurons, the pivotal neuronal population that degenerates in …