Hyperglycaemia that develops during pregnancy and resolves after birth has been
recognized for over 50 years, but uniform worldwide consensus is lacking about threshold …

Maturity-onset diabetes of the young (MODY) is characterized by autosomal dominant
inheritance, onset before 25 years of age, absence of β-cell autoimmunity, and sustained …

Monogenic diabetes results from one or more defects in a single gene. The disease may be
inherited within families as a dominant, recessive or non-Mendelian trait or may present as a …

ISPAD Clinical Practice Consensus Guidelines 2022: The diagnosis and management of
monogenic diabetes in children and adolescents - PMC Back to Top Skip to main content NIH …

Background The most common type of monogenic diabetes is maturity-onset diabetes of the
young (MODY), a clinically and genetically heterogeneous group of endocrine disorders that …

Maturity-onset diabetes of the young, or MODY-monogenic diabetes, is a not-so-rare
collection of inherited disorders of non-autoimmune diabetes mellitus that remains …

Aims: Our study aims were to determine the frequency of MODY mutations (HNF1A, HNF4A,
glucokinase) in a diverse population of youth with diabetes and to assess how well clinical …

Aims/hypothesis Maturity-onset diabetes of the young is frequently misdiagnosed as type 1
or type 2 diabetes. A correct diagnosis of MODY is important for determining treatment, but …

Glucokinase is a key regulatory enzyme in the pancreatic beta‐cell. It plays a crucial role in
the regulation of insulin secretion and has been termed the glucose sensor in pancreatic …

EARLY HISTORY—In the academic year 1949–1950, one of us (SSF), while a first-year
Fellow in Endocrinology and Metabolism at the University of Michigan (Jerome W. Conn …