Fused bicyclic 1, 2, 4‐triazoles with one extra sulfur atom: Synthesis, properties, and biological activity

MV Slivka, NI Korol, MM Fizer - Journal of Heterocyclic …, 2020 - Wiley Online Library
Abstract Fused heterocyclic systems with 1, 2, 4‐triazole scaffold arouse great interest from
researchers in the branch of heterocyclic and medical chemistry because of their wide …

The use of electrophilic cyclization for the preparation of condensed heterocycles

M Slivka, M Onysko - Synthesis, 2021 - thieme-connect.com
Condensed heterocycles are well-known for their excellent biological effects and they are
undeniably important compounds in organic chemistry. Electrophilic cyclization reactions …

Regio- and stereoselective synthesis of [1,3]thiazolo[3,2-b][1,2,4]triazol-7-ium salts via electrophilic heterocyclization of 3-S-propargylthio-4Н-1,2,4-triazoles and …

M Slivka, N Korol, V Pantyo, V Baumer… - Heterocyclic …, 2017 - degruyter.com
A procedure for the preparation of the title salts via regioselective halocyclization of 3-S-
propargylthio-4 Н-1, 2, 4-triazoles is reported. Stereoselectivity of electrophilic …

Halo-heterocyclization of butenyl(prenyl)thioethers of 4,5-diphenyl-1,2,4-triazol-3-thiole into triazolo[5,1-b] [1,3]thiazinium systems: experimental and theoretical …

N Korol, M Slivka, M Fizer, V Baumer… - Monatshefte für Chemie …, 2020 - Springer
A facile and highly efficient regioselective synthesis of partially saturated triazolo [5, 1-b][1, 3]
thiazinium salts by the electrophilic heterocyclization of the butenyl thioethers of 4, 5 …

[1,3]Thiazolo[3,2-b][1,2,4]triazol-7-ium salts: synthesis, properties and structural studies

M Slivka, N Korol, M Fizer, V Baumer… - Heterocyclic …, 2018 - degruyter.com
Abstract The reactions of [1, 3] thiazolo [3, 2-b][1, 2, 4] triazol-7-ium salts with nucleophiles
were investigated. Theoretical investigation of reactivity descriptors and structural …

Recent progress in the synthesis of thiazolo[3,2-b][1,2,4]triazoles (microreview)

NI Korol, MV Slivka - Chemistry of Heterocyclic Compounds, 2017 - Springer
A summary of the most recent approaches toward synthesis of thiazolo [3, 2-b][1, 2, 4]
triazole system is reported. The microreview covers the latest selected examples on the …

[1,3]Thiazolo[2′,3′:3,4][1,2,4]triazolo[1,5‐a]pyrimidines – A New Heterocyclic System Accessed via Bromocyclization

M Fizer, M Slivka, E Rusanov, A Turov… - Journal of Heterocyclic …, 2015 - Wiley Online Library
A facile access to novel condensed system of [1, 3] thiazolo [2′, 3′: 3, 4][1, 2, 4] triazolo [1,
5‐a] pyrimidine is presented. This protocol consists of bromine‐assisted direct electrophilic …

Synthesis of [1, 3] thiazolo [3, 2-b][1, 2, 4] triazol-7-ium and [1, 2, 4] triazolo [5, 1-b][1, 3] thiazin-4-ium salts via regioselective electrophilic cyclization of 3-[(2-alken-1-yl) …

M Slivka, N Korol, I Rusyn, V Lendel - Heterocyclic Communications, 2015 - degruyter.com
A convenient procedure for the regioselective preparation of [1, 3] thiazolo [3, 2-b][1, 2, 4]
triazol-7-ium 10 and [1, 2, 4] triazolo [5, 1-b][1, 3] thiazin-4-ium salts 9 via regioselective …

Stereoselective synthesis of (E)-halomethylidene [1, 3] thiazolo [3, 2-a] thieno [3, 2-e] pyrimidinium and analogous [1, 3] oxazolo [3, 2-a] thieno [3, 2-e] pyrimidinium …

M Slivka, A Krivovjaz, M Slivka… - Heterocyclic …, 2013 - degruyter.com
A convenient procedure for the stereoselective synthesis of [1, 3] thiazolo [3, 2-a] thieno [3, 2-
e] pyrimidinium halides and analogous [1, 3] oxazolo [3, 2-a] thieno [3, 2-e] pyrimidinium …

Synthesis of novel fluorine-and iodine-containing [1, 2, 4] triazolo [3, 4-b][1, 3] thiazines based 3-(alkenylthio)-5-(trifluoromethyl)-4H-1, 2, 4-triazole-3-thiols

ES Il'inykh, DG Kim, MI Kodess, EG Matochkina… - Journal of Fluorine …, 2013 - Elsevier
In this paper we report the synthesis of novel S-alkenyl derivatives of 5-(trifluoromethyl)-4H-
1, 2, 4-triazole-3-thiol via alkenation reaction with different alkenyl halides. Reaction …