All cancers tested so far display abnormal choline and ethanolamine phospholipid
metabolism, which has been detected with numerous magnetic resonance spectroscopy …

Phospholipids represent a crucial component for the structure of cell membranes.
Phosphatidylcholine and phosphatidylethanolamine are two phospholipids that comprise …

Cholesterol oxidation products, also named oxysterols, can be formed either by cholesterol
auto-oxidation, enzymatically or both. Among these oxysterols, 7-ketocholesterol (7KC) is …

Aging is defined as the accumulation of progressive organ dysfunction. There is much
evidence linking the involvement of oxidative stress in the pathogenesis of aging. With …

Lymph node metastasis was recently proven to be the single most important prognostic
factor for esophageal cancer, an important malignant tumor with poor prognosis. A global …

Cancer is the second leading cause of mortality worldwide. The role of unresolved
inflammation in cancer progression and metastasis is well established. Platelet-activating …

Recent advances in biological imaging techniques and the enormous amount of data they
generate call for the development of computational tools for efficient and reliable high …

Angiogenesis plays a fundamental role in tumor development, as it is crucial for tumor
progression, metastasis development, and invasion. In this view, anti-angiogenic therapy …

7-Ketocholesterol (7-KC) is a cholesterol oxidation product with several biological functions.
7-KC has the capacity to cause cell death depending on the concentration and specific cell …

Oxysterols are 27-carbon oxidation products of cholesterol metabolism. Oxysterols possess
several biological actions, including the promotion of cell death. Here, we examined the …