Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …

Herpes simplex virus type 1 (HSV-1) is highly prevalent in humans and can reach the brain
without evident clinical symptoms. Once in the central nervous system (CNS), the virus can …

Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for
which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 …

Alphaherpesviruses (α-HV) are a large family of double-stranded DNA viruses which cause
many human and animal diseases. There are three human α-HVs: Herpes Simplex Viruses …

Herpes simplex virus (HSV) establishes a latent infection in peripheral neurons and can
periodically reactivate to cause disease. Reactivation can be triggered by a variety of stimuli …

During herpes simplex virus (HSV) latency, the viral genome is harbored in peripheral
neurons in the absence of infectious virus but with the potential to restart infection. Advances …

Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a
lifelong latent infection in the human host. Following primary replication in mucosal epithelial …

Herpes labialis remains exceedingly prevalent and is one of the most common human viral
infections throughout the world. Recurrent herpes labialis evolves from the initial viral …

Herpes simplex virus (HSV) keratitis is one of the leading causes of blindness worldwide.
Additionally, up to 90% of the population in some countries is seropositive for HSV. HSV can …

Abstract Varicella-zoster virus (VZV), an alphaherpesvirus, establishes lifelong latent
infection in the neurons of> 90% humans worldwide, reactivating in one-third to cause …