Abstract Fused heterocyclic systems with 1, 2, 4‐triazole scaffold arouse great interest from
researchers in the branch of heterocyclic and medical chemistry because of their wide …

Over the past decades, a tremendous rise in invasive fungal infection diseases attributed to
the yeast Candida albicans in immunocompromised individuals poses a seriously …

We studied the reaction of enaminone 3 with some nitrogen nucleophiles to afford the
corresponding pyrazole 4, isoxazole 5, and pyrimidine 6 derivatives, and the reactivity of …

Herein, a series of N'-benzylidene-3, 4-dimethoxybenzohydrazide derivatives were
designed and synthesised to target the multidrug efflux pump (MATE). The antibacterial …

A new series of 1, 2, 3-triazole derivatives 5a–f based on benzothiazole were synthesized by
the 1, 3-dipolar cycloaddition reaction of S-propargyl mercaptobenzothiazole and α-halo …

Background: Inflammation is a complex response to noxious stimuli promoted by the release
of chemical mediators from the damaged cells. Metabolic products of arachidonic acid …

The present paper is devoted to the search for drug-like molecules with anticancer
properties using the thiazolo [3, 2-b][1, 2, 4] triazole-6-one scaffold. A series of 24 novel …

The emergence of antibiotic resistance highlights the critical need for novel antimicrobial
agents. In this study, we investigated the synthesis of methyl α-D-glucopyranoside (1) …

The search for new antimicrobial agents is greater than ever due to the perpetual threat of
multidrug resistance in known pathogens and the relentless emergence of new infections. In …

triazole derivatives exhibit various biological activities, including antibacterial and antifungal
properties. On the other hand, these chemicals may have unique cumulative and harmful …