Pharmaceutical applications of lignin-derived chemicals and lignin-based materials: Linking lignin source and processing with clinical indication

P Karagoz, S Khiawjan, MPC Marques… - Biomass Conversion …, 2023 - Springer
Lignocellulosic biomass is one of the most abundant bioresources on Earth. Over recent
decades, various valorisation techniques have been developed to produce value-added …

Bio-based valorization of lignin-derived phenolic compounds: a review

L Martínková, M Grulich, M Pátek, B Křístková… - Biomolecules, 2023 - mdpi.com
Lignins are the most abundant biopolymers that consist of aromatic units. Lignins are
obtained by fractionation of lignocellulose in the form of “technical lignins”. The …

[HTML][HTML] Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation

Q Wu, W Li, J Zhao, W Sun, Q Yang, C Chen… - Biomedicine & …, 2021 - Elsevier
Background and objective Doxorubicin (DOX) is an anthracycline antitumor antibiotic widely
utilized in treating various tumors. Nevertheless, the toxicity of DOX toward normal cells …

[HTML][HTML] Vanillin: A food additive with multiple biological activities

A Olatunde, A Mohammed, MA Ibrahim… - European Journal of …, 2022 - Elsevier
Abstract Vanillin (4-hydroxy-3-methoxybenzaldehyde) is a known natural aromatic
flavouring agent and the major component of vanilla extracted from cured vanilla pods …

Artificial neural network approach for prediction of AuNPs biosynthesis by Streptomyces flavolimosus, characterization, antitumor potency in-vitro and in-vivo against …

NEA El-Naggar, NH Rabei, MF Elmansy… - Scientific Reports, 2023 - nature.com
Gold nanoparticles (AuNPs) have emerged as promising and versatile nanoparticles for
cancer therapy and are widely used in drug and gene delivery, biomedical imaging …

Vanillin augments liver regeneration effectively in Thioacetamide induced liver fibrosis rat model

AMH Ghanim, NS Younis, HA Metwaly - Life Sciences, 2021 - Elsevier
Aims This study has been designed to investigate the role of vanillin either as prophylaxis or
treatment in liver regeneration augmentation and liver fibrosis regression in thioacetamide …

Suppression of VEGF and inflammatory cytokines, modulation of Annexin A1 and organ functions by galloylquinic acids in breast cancer model

M Abd El-Salam, G El-Tanbouly, J Bastos… - Scientific Reports, 2023 - nature.com
The ongoing development of novel drugs for breast cancer aims to improve therapeutic
outcomes, reduce toxicities, and mitigate resistance to chemotherapeutic agents …

Impact of the Cancer Cell Secretome in driving breast Cancer progression

S Zahari, SE Syafruddin, MA Mohtar - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is a complex disease that remains a significant public health
challenge. The breast cancer cells secrete various substances collectively known as the …

Vanillin prevents the growth of endometriotic lesions through anti-inflammatory and antioxidant pathways in a mouse model

YN Liu, JW Kang, Y Zhang, SS Song, QX Xu… - Food & Function, 2023 - pubs.rsc.org
Endometriosis is an estrogen-dependent chronic inflammatory gynecological disease
defined by the presence of endometrial glands and mesenchyme outside the uterine cavity …

Targeting cyclin‐dependent kinase 6 by vanillin inhibits proliferation of breast and lung cancer cells: Combined computational and biochemical studies

M Yousuf, A Shamsi, A Queen… - Journal of Cellular …, 2021 - Wiley Online Library
Abstract Cyclin‐dependent kinase 6 (CDK6) is a member of serine/threonine kinase family,
and its overexpression is associated with cancer development. Thus, it is considered as a …