Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - Elsevier
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Neuroinflammation and central sensitization in chronic and widespread pain

RR Ji, A Nackley, Y Huh, N Terrando… - …, 2018 - pmc.ncbi.nlm.nih.gov
Chronic pain is maintained in part by central sensitization, a phenomenon of synaptic
plasticity and increased neuronal responsiveness in central pain pathways after painful …

A neuroanatomical basis for electroacupuncture to drive the vagal–adrenal axis

S Liu, Z Wang, Y Su, L Qi, W Yang, M Fu, X Jing… - Nature, 2021 - nature.com
Somatosensory autonomic reflexes allow electroacupuncture stimulation (ES) to modulate
body physiology at distant sites,,,,–(for example, suppressing severe systemic inflammation …

[HTML][HTML] Somatotopic organization and intensity dependence in driving distinct NPY-expressing sympathetic pathways by electroacupuncture

S Liu, ZF Wang, YS Su, RS Ray, XH Jing, YQ Wang… - Neuron, 2020 - cell.com
The neuroanatomical basis behind acupuncture practice is still poorly understood. Here, we
used intersectional genetic strategy to ablate NPY+ noradrenergic neurons and/or adrenal …

Pain regulation by non-neuronal cells and inflammation

RR Ji, A Chamessian, YQ Zhang - Science, 2016 - science.org
Acute pain is protective and a cardinal feature of inflammation. Chronic pain after arthritis,
nerve injury, cancer, and chemotherapy is associated with chronic neuroinflammation, a …

Mechanisms and therapeutic relevance of neuro-immune communication

SS Chavan, VA Pavlov, KJ Tracey - Immunity, 2017 - cell.com
Active research at the frontiers of immunology and neuroscience has identified multiple
points of interaction and communication between the immune system and the nervous …

Molecular and functional neuroscience in immunity

VA Pavlov, SS Chavan, KJ Tracey - Annual review of …, 2018 - annualreviews.org
The nervous system regulates immunity and inflammation. The molecular detection of
pathogen fragments, cytokines, and other immune molecules by sensory neurons generates …

Anti-inflammatory effects of acupuncture at ST36 point: a literature review in animal studies

JE Oh, SN Kim - Frontiers in Immunology, 2022 - frontiersin.org
So far, a number of acupuncture studies have shown anti-inflammatory effects of
acupuncture treatment, mostly known at specific point ST36. However, there is no literature …

Sepsis therapies: learning from 30 years of failure of translational research to propose new leads

JM Cavaillon, M Singer, T Skirecki - EMBO molecular medicine, 2020 - embopress.org
Sepsis has been identified by the World Health Organization (WHO) as a global health
priority. There has been a tremendous effort to decipher underlying mechanisms …

[HTML][HTML] Understandings of acupuncture application and mechanisms

JG Lin, P Kotha, YH Chen - American journal of translational …, 2022 - ncbi.nlm.nih.gov
Acupuncture involves the stimulation of acupoints, which are located at specific sites of the
human body, by insertion of fine metal needles, followed by manipulation. Acupuncture has …